ArticleBrain imaging and behavior2013
DTI tractography and white matter fiber tract characteristics in euthymic bipolar I patients and healthy control subjects.
Article in Brain imaging and behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- White Matter Tract Alterations in Bipolar Disorder: A Systematic Review and Meta-Analysis of Diffusion Tensor Imaging Studies.Brain and behavior · 2026Pooled it
- Neurobiological underpinnings of bipolar disorder focusing on findings of diffusion tensor imaging: a systematic review.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2016Pooled it
- Comparison of tibial and femoral physeal diffusion tensor imaging in adolescents.Pediatric radiology · 2024Article
- Alterations of Structural Network Efficiency in Early-Onset and Late-Onset Alzheimer's Disease.Journal of clinical neurology (Seoul, Korea) · 2024Article
- Diffusion tensor imaging of the physis: the ABC's.Pediatric radiology · 2023Review
- Genetic architecture of the white matter connectome of the human brain.Science advances · 2023Article
- Changes in the superior longitudinal fasciculus and anterior thalamic radiation in the left brain are associated with developmental dyscalculia.Frontiers in human neuroscience · 2023Article
- The Limits between Schizophrenia and Bipolar Disorder: What Do Magnetic Resonance Findings Tell Us?Behavioral sciences (Basel, Switzerland) · 2022Review
- Treatment outcome of posttraumatic stress disorder: A white matter tract analysis.Journal of anxiety disorders · 2021Article
- Exploring Signatures of Neurodegeneration in Early-Onset Older-Age Bipolar Disorder and Behavioral Variant Frontotemporal Dementia.Frontiers in neurology · 2021Article
- Disrupted Rich Club Organization of Hemispheric White Matter Networks in Bipolar Disorder.Frontiers in neuroinformatics · 2020Article
- Big data sharing and analysis to advance research in post-traumatic epilepsy.Neurobiology of disease · 2019Review
- White matter - emotion processing activity relationships in youth offspring of bipolar parents.Journal of affective disorders · 2019Article
- The superior longitudinal fasciculus and its functional triple-network mechanisms in brooding.NeuroImage. Clinical · 2019Article
- Age-Related Alterations of White Matter Integrity in Adolescents and Young Adults With Bipolar Disorder.Frontiers in psychiatry · 2019Article
- Age-specific effects of structural and functional connectivity in prefrontal-amygdala circuitry in women with bipolar disorder.BMC psychiatry · 2018Article
- Kynurenine pathway and white matter microstructure in bipolar disorder.European archives of psychiatry and clinical neuroscience · 2018Article
- Longitudinal Diffusion Tensor Imaging Study of Adolescents and Young Adults With Bipolar Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2018Article
- Aberrant Anterior Thalamic Radiation Structure in Bipolar Disorder: A Diffusion Tensor Tractography Study.Frontiers in psychiatry · 2018Article
- White Matter Microstructural Changes and Episodic Memory Disturbances in Late-Onset Bipolar Disorder.Frontiers in psychiatry · 2018Article
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9 authors.
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Abstract
With the introduction of diffusion tensor imaging (DTI), structural differences in white matter (WM) architecture between psychiatric populations and healthy controls can be systematically observed and measured. In particular, DTI-tractography can be used to assess WM characteristics over the entire extent of WM tracts and aggregated fiber bundles. Using 64-direction DTI scanning in 27 participants with bipolar disorder (BD) and 26 age-and-gender-matched healthy control subjects, we compared relative length, density, and fractional anisotrophy (FA) of WM tracts involved in emotion regulation or theorized to be important neural components in BD neuropathology. We interactively isolated 22 known white matter tracts using region-of-interest placement (TrackVis software program) and then computed relative tract length, density, and integrity. BD subjects demonstrated significantly shorter WM tracts in the genu, body and splenium of the corpus callosum compared to healthy controls. Additionally, bipolar subjects exhibited reduced fiber density in the genu and body of the corpus callosum, and in the inferior longitudinal fasciculus bilaterally. In the left uncinate fasciculus, however, BD subjects exhibited significantly greater fiber density than healthy controls. There were no significant differences between groups in WM tract FA for those tracts that began and ended in the brain. The significance of differences in tract length and fiber density in BD is discussed.
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