ReviewCurrent diabetes reports2012
The epigenome and its role in diabetes.
Review in Current diabetes reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Diabetes Study of Children of Diverse Ethnicity and Race: Study design.Diabetes/metabolism research and reviews · 2024Observational
- Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study.Epigenetics · 2020Article
- Association between DNA Methylation in Whole Blood and Measures of Glucose Metabolism: KORA F4 Study.PloS one · 2016Article
- Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016Review
- Genetic and epigenetic modifications in the pathogenesis of diabetic retinopathy: a molecular link to regulate gene expression.New frontiers in ophthalmology (London) · 2016Article
- Intrauterine Programming of Diabetes and Adiposity.Current obesity reports · 2015Review
- Obese first-degree relatives of patients with type 2 diabetes with elevated triglyceride levels exhibit increased β-cell function.Metabolic syndrome and related disorders · 2015Article
- New insights from monogenic diabetes for "common" type 2 diabetes.Frontiers in genetics · 2015Review
- Integrating transcriptome and epigenome: putting together the pieces of the type 2 diabetes pathogenesis puzzle.Diabetes · 2014Article
- Personalized nutrition and obesity.Annals of medicine · 2014Review
- Potential mechanisms of aberrant DNA hypomethylation on the x chromosome in uterine leiomyomas.The Journal of reproduction and development · 2014Article
- Social epidemiology of diabetes and associated conditions.Current diabetes reports · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Both genetic and environmental factors play critical roles in the development of diabetes. Epidemiological evidence and data from clinical studies suggest the persistence of a "metabolic memory" of past exposures to environmental factors or glycemic control. Epigenetic mechanisms are regarded as one of the likeliest candidates underlying these phenomena. On the other hand, owing to the recent elucidation of mechanisms that erase epigenetic marks, it has gradually become recognized that epigenetic regulation is a more dynamic process than previously thought. A technological breakthrough in epigenome research in the past decade was the development of high-throughput sequencing. This new technology lets us investigate the epigenome in a global and comprehensive manner, and provides previously unrecognized findings and insights. This review presents an overview of the recent progress in our understanding of epigenetic regulation in type 1 and type 2 diabetes research.
Indexed as
Identifiers
23070559What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.