Evidence map›Paper›PMID 23070276›Full record

ReviewPediatric nephrology (Berlin, Germany)2013

Cardiovascular risk assessment in children with chronic kidney disease.

Rukshana Shroff, Arianna Dégi, Andrea Kerti, Eva Kis, Orsolya Cseprekál, Kálmán Tory, Attila J Szabó, George S Reusz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Subclinical Organ Damage in Children and Adolescents with Hypertension: Current Guidelines and Beyond.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2019
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Chronic kidney disease in children.Clinical kidney journal · 2016
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Rukshana ShroffRenal Unit, Great Ormond Street Hospital for Children, London, UK.
Arianna Dégi
Andrea Kerti
Eva Kis
Orsolya Cseprekál
Kálmán Tory
Attila J Szabó
George S Reusz
Semmelweis University · HUUniversity College London · GB

Funding

British Heart Foundation
6 · The paper itself

Abstract

Chronic kidney disease (CKD) is a major factor contributing to cardiovascular (CV) morbidity and mortality with the highest risk in patients on dialysis. An estimation of CV risk is important not only to identify potential modifiable risk factors but also to evaluate the effect of treatments aimed to reduce the risk. Non-invasive methods of measuring vascular changes and circulating biomarkers are available to assess the presence and severity of cardiovascular damage. These include measures of structural (carotid intima-media thickness and coronary artery calcification score) and functional (aortic pulse wave velocity, 24-h ambulatory blood pressure monitoring, ambulatory arterial stiffness index, heart rate variability and flow-mediated dilatation) changes in the vessel wall. In addition, a number of circulating biomarkers of vascular damage and its progression have been studied. Many of these tests are well validated as surrogate markers of future cardiovascular events and death in adult CKD patients, but need technical adaptation, standardization and validation for use in children. With our current state of knowledge, these are best reserved for research studies and scarce clinical resources may be better utilized for preventative strategies to reduce the modifiable risk factors for calcification from early CKD stages.

Indexed as

Risk AssessmentAdolescentBlood Pressure Monitoring, AmbulatoryCalcium-Binding ProteinsCardiovascular DiseasesCarotid Intima-Media ThicknessChildElasticityExtracellular Matrix ProteinsHeart RateHumansMatrix Gla ProteinPulse Wave AnalysisRenal Insufficiency, ChronicVascular CalcificationVascular StiffnessCalcium-Binding ProteinsExtracellular Matrix ProteinsMatrix Gla Protein

Identifiers

PMID23070276
OpenAlexW2105439345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.