ArticleDiabetes care2013
No ethnic differences in the association of glycated hemoglobin with retinopathy: the national health and nutrition examination survey 2005-2008.
Article in Diabetes care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Diagnosing type 2 diabetes using Hemoglobin A1c: a systematic review and meta-analysis of the diagnostic cutpoint based on microvascular complications.Acta diabetologica · 2021Pooled it
- Effect of ethnicity on HbA1c levels in individuals without diabetes: Systematic review and meta-analysis.PloS one · 2017Pooled it
- Prevalence of Retinopathy in Prediabetic Populations: A Systematic Review and Meta-Analysis.Cureus · 2023Review
- Optimizing treatment goals for long-term health outcomes among patients with type 2 diabetes mellitus.BMJ open diabetes research & care · 2021Article
- The trials and tribulations of determining HbANature reviews. Endocrinology · 2020Review
- Retinopathy develops at similar glucose levels but higher HbADiabetic medicine : a journal of the British Diabetic Association · 2020Article
- Racial differences in performance of HbADiabetic medicine : a journal of the British Diabetic Association · 2019Article
- The National Glycohemoglobin Standardization Program: Over 20 Years of Improving Hemoglobin AClinical chemistry · 2019Review
- Diabetic Retinopathy: Focus on Minority Populations.International journal of clinical endocrinology and metabolism · 2017Article
- Evidence for current diagnostic criteria of diabetes mellitus.World journal of diabetes · 2016Review
- Are There Clinical Implications of Racial Differences in HbA1c? A Difference, to Be a Difference, Must Make a Difference.Diabetes care · 2016Article
- Are There Clinical Implications of Racial Differences in HbA1c? Yes, to Not Consider Can Do Great Harm!Diabetes care · 2016Article
- Racial Differences in and Prognostic Value of Biomarkers of Hyperglycemia.Diabetes care · 2016Article
- Should haemoglobin A1C be used for diagnosis of diabetes mellitus in Malawi?Malawi medical journal : the journal of Medical Association of Malawi · 2016Article
- 2015 Presidential Address: 75 Years of Battling Diabetes--Our Global Challenge.Diabetes care · 2016Article
- Risk Factors for Proliferative Diabetic Retinopathy in African Americans with Type 2 Diabetes.Ophthalmic epidemiology · 2016Article
- Interpreting Hemoglobin A1C in Combination With Conventional Risk Factors for Prediction of Cardiovascular Risk.Circulation. Cardiovascular quality and outcomes · 2015Article
- Diabetes Complications at Presentation and One Year by Glycated Haemoglobin at Diagnosis in a Multiethnic and Diverse Socioeconomic Population: Results from the South London Diabetes Study.Journal of diabetes research · 2015Article
- Article
- Trends in prevalence and control of diabetes in the United States, 1988-1994 and 1999-2010.Annals of internal medicine · 2014Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveCurrent recommendations for the use of hemoglobin A(1c) (HbA(1c)) in diabetes screening and diagnosis aim to identify those at greatest risk for diabetic microvascular complications. However, there is current controversy regarding the clinical implications of ethnic differences in HbA(1c) values. The objective of this study was to determine whether the association between HbA(1c) and retinopathy differs by ethnic group in a representative sample of U.S. adults. RESEARCH DESIGN AND
methodsThe study was a cross-sectional analysis of 2,945 non-Hispanic white, 1,046 non-Hispanic black, and 1,231 Hispanic American participants aged ≥40 years from the 2005-2008 National Health and Nutrition Examination Survey.
resultsAmong nondiabetic adults, the mean HbA(1c) was 5.5% in non-Hispanic whites, 5.7% in non-Hispanic blacks, and 5.6% in Hispanic Americans. Among those with diagnosed diabetes, mean HbA(1c) was 6.9% in non-Hispanic whites, 7.5% in non-Hispanic Blacks, and 7.7% in Hispanic Americans. Overall, non-Hispanic blacks had the highest prevalence of retinopathy. In multivariable logistic models, HbA(1c) clinical categories were strongly associated with prevalent retinopathy. However, the magnitude of the association did not differ by ethnic group (all P values for interaction ≥ 0.7). Similar results were observed with HbA(1c) modeled continuously (per one percentage point) and stratified by diabetes status (all P for interactions > 0.3).
conclusionsWe observed no ethnic differences in the association of HbA(1c) with retinopathy. These data do not support ethnic-specific cut points for HbA(1c) for diagnosis or screening of diabetes mellitus.
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Registered trials
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