ArticleBMJ open2012
Childhood adversities and adult-onset asthma: a cohort study.
Article in BMJ open, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Adverse childhood experience and asthma onset: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2015Pooled it
- The Relationship Between Childhood Trauma and Interpersonal Relationship Dimensions in Individuals with Generalized Anxiety Disorder: The Mediating Role of Anger Rumination.Psychiatry and clinical psychopharmacology · 2025Article
- Integrating Trauma-Informed Care into the University of Kansas School of Medicine Utilizing the Curriculum, a Student Interest Group, and Community Partnerships.Kansas journal of medicine · 2024Article
- Early Adverse Experiences and Repeated Wheezing From 6 to 30 Months of Age: Investigating the Roles of Hypothalamic-Pituitary-Adrenal Axis Functioning, Child Sex, and Caregiving Sensitivity.Child development · 2021Article
- Adverse childhood experiences and chronic lung diseases in adulthood: a systematic review and meta-analysis.European journal of psychotraumatology · 2020Review
- Self Reported Childhood Difficulties, Adult Multimorbidity and Allostatic Load. A Cross-Sectional Analysis of the Norwegian HUNT Study.PloS one · 2015Article
- Association between mental disorders and subsequent adult onset asthma.Journal of psychiatric research · 2014Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesChildhood adversities may be important determinants of later illnesses and poor health behaviour. However, large-scale prospective studies on the associations between childhood adversities and the onset of asthma in adulthood are lacking.
designProspective cohort study with 7-year follow-up.
settingNationally representative study. Data were collected from the Health and Social Support (HeSSup) survey and national registers.
participantsThe participants represent the Finnish population from the following age groups: 20-24, 30-34, 40-44, and 50-54 years at baseline in 1998 (24 057 survey participants formed the final cohort of this study). The occurrence of childhood adversities was assessed at baseline with a six-item survey scale. The analyses were adjusted for sociodemographic characteristics, behavioural health risks and common mental disorders. PRIMARY AND SECONDARY OUTCOMES: The survey data were linked to data from national health registers on incident asthma during a 7-year follow-up to define new-onset asthma cases with verified diagnoses.
resultsA total of 12 126 (59%) participants reported that they encountered a childhood adversity. Of them 3677 (18% of all) endured three to six adversities. During a follow-up of 7 years, 593 (2.9%) participants were diagnosed with incident asthma. Those who reported three or more childhood adversities had a 1.6-fold (95% CI 1.31 to 2.01) greater risk of asthma compared to those without childhood adversities. This hazard attenuated but remained statistically significant after adjustment for conventional risk factors (HR 1.33; 95% CI 1.06 to 1.67).
conclusionsAdults who report having encountered adversities in childhood may have an increased risk of developing asthma.
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Registered trials
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