Evidence map›Paper›PMID 23067148›Full record

ArticleJournal of the American Chemical Society2012

Concentration-independent pH detection with a luminescent dimetallic Eu(III)-based probe.

Jeremiah D Moore, Richard L Lord, G Andrés Cisneros, Matthew J Allen

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. HNature communications · 2020
    Article
  3. Article
  4. Article
  5. Aqueous Lanthanide Chemistry in Asymmetric Catalysis and Magnetic Resonance Imaging.Synlett : accounts and rapid communications in synthetic organic chemistry · 2016
    Article
  6. Article
  7. Aqueous Eu(II)-Containing Complex with Bright Yellow Luminescence.Journal of the American Chemical Society · 2015
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeremiah D MooreDepartment of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.
Richard L Lord
G Andrés Cisneros
Matthew J Allen

Funding

2012 Metals in Medicine Gordon Research ConferenceR13EB015773 · NIBIB · GORDON RESEARCH CONFERENCES · PI SHERRY, DEAN · 2012 to 2012
$15k
NIBIB NIH HHS 1R13EB015773-01NIBIB NIH HHS R13 EB015773
6 · The paper itself

Abstract

A pH-responsive, luminescent, dimetallic Eu(III)-containing complex has been synthesized and exhibits a unique mechanism of response. The luminescence-decay rate of the complex is slow, due to a lack of water molecules coordinated to the Eu(III) ions. However, the luminescence-decay rate decreases with increasing pH over a biologically relevant range of 4-8. Physical characterization and computational analysis suggest that the pH response is due to protonation of a bridging alkoxide at lower pH values. Modulation of the luminescence-decay rate is independent from the concentration of Eu(III), which we expect to be useful in the non-invasive imaging of in vivo pH.

Indexed as

LuminescenceCoordination ComplexesEuropiumHydrogen-Ion ConcentrationLuminescent AgentsModels, MolecularMolecular StructureCoordination ComplexesEuropiumLuminescent Agents

Identifiers

PMID23067148
PMCPMC3492840

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.