ArticleHelicobacter2013
The epidemiology, diagnosis, and cost of dyspepsia and Helicobacter pylori gastritis: a case-control analysis in the Southwestern United States.
Article in Helicobacter, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Pooled it
- Correlation of endoscopic findings, histopathological features and Helicobacter pylori infection in adult dyspeptic patients from the cold desert tribal region of Spiti Valley, Himachal Pradesh.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Observational
- Healthcare costs of foodborne diseases in the United States: an analysis using electronic health records.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Accuracy of Stool Antigen Test in the Diagnosis of Helicobacter pylori Infection in the Dominican Republic.Cureus · 2023Article
- Endoscopic and histopathological findings in adult dyspeptic patients, and their association withIJID regions · 2022Article
- Article
- Diagnosis and Comparison of Three Invasive Detection Methods for Helicobacter pylori Infection.Microbiology insights · 2022Article
- Prevalence and risk factors ofAmerican journal of translational research · 2022Article
- Comparison of clinical symptoms afterNew microbes and new infections · 2020Article
- Time Trends in Healthcare Utilization Due to Self-Reported Functional Diseases of the Stomach.Digestive diseases and sciences · 2020Article
- Guideline Adherence in Dyspepsia Investigation and Treatment.Kansas journal of medicine · 2020Article
- Ethnic, Racial, and Sex Differences in Etiology, Symptoms, Treatment, and Symptom Outcomes of Patients With Gastroparesis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2019Observational
- Reciprocal impact of host factors and Helicobacter pylori genotypes on gastric diseases.World journal of gastroenterology · 2015Article
- Gastric polyps: Association with Helicobacter pylori status and the pathology of the surrounding mucosa, a cross sectional study.World journal of gastrointestinal endoscopy · 2015Article
- Prevalence of Helicobacter pylori in Patients With Dyspepsia.Jundishapur journal of microbiology · 2014Article
- Helicobacter pylori: evidence-based review with a focus on immigrant populations.Journal of general internal medicine · 2014Review
- Autoimmune atrophic gastritis--pathogenesis, pathology and management.Nature reviews. Gastroenterology & hepatology · 2013Review
- Helicobacter pylori seropositivity and cognitive performance among US adults: evidence from a large national survey.Psychosomatic medicine · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDyspepsia is among the most common complaints evaluated by gastroenterologists, but there are few studies examining its current epidemiology, evaluation, and costs. We examined these issues in a large managed care system in the Southwestern United States.
methodsWe conducted a retrospective case-control analysis of adults with incident dyspepsia or a Helicobacter pylori-related condition in years 2006 through 2010 using utilization data. Medical record abstraction of 400 cases was conducted to obtain additional clinical information.
resultsA total of 6989 cases met all inclusion and exclusion criteria. Women had a substantially higher risk of dyspepsia than men (14 per 1000 per year vs 10 per 1000; p < .001), and the incidence of dyspepsia increased with age such that persons in their seventh decade had almost twice the risk of those aged 18-29. Hispanic persons had a significantly higher risk of dyspepsia and positive H. pylori testing. Dyspepsia cases had a higher prevalence of other chronic comorbidities than their matched controls. Dyspepsia patients had healthcare costs 54% higher than controls even before the diagnosis was made, and costs in the initial diagnostic period were $483 greater per person, but subsequent costs were not greatly affected. Among those aged 55 and younger, the "test and treat" approach was used in 53% and another 18% had an initial esophagogastroduodenoscopy, as compared to 47 and 27%, respectively, among those over the age of 55.
conclusionsWomen and older adults have a higher incidence of dyspepsia than previously appreciated, and Hispanics in this region also have a higher risk. Current guidelines for dyspepsia evaluation are only loosely followed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.