Effect of Magnetospirillum gryphiswaldense on serum iron levels in mice.

T Setayesh, Sf Mousavi, Sd Siadat

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In one paragraph

Article in Iranian journal of microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 89% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

T SetayeshMicrobiology Research Center & Department of Bacteriology, Pasteur Institute of Iran, Pasteur Ave., Tehran, Iran ; Microbiology Group, Islamic Azad University of Tonekabon, Tonekabon Iran.

Sf Mousavi

Sd Siadat

Pasteur Institute of Iran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe Magnetotactic bacterium Magnetospirillumgryphiswaldense (MSR-1) mineralizes the magnetite (Fe(3) O(4)) crystals and organizes a highly ordered intracellular structure, called the magnetosome. Iron transport system supports the biogenesis of magnetite. Although iron is an essential trace element for many metabolic pathways of the body, increase or decrease in iron will cause many diseases. Mice were infected by MSR-1 to study survival of bacteria in mice when injected by different routes. The aim of this study was to investigate whether bacterial magnetite formation could take up Fe(2+) ions from the blood an animal model. MATERIAL AND

methodsIn this study, MSR-1 at a dose lower than LD(50) in 200 µl volume of PBS buffer was injected as intravascular (i.v), peritoneal (i.p) and subcutaneous (s.c) in mice. Number of viable bacterial was determined in organs such as liver, spleen and lymph node by measuring colony-forming unit (CFU). Moreover, serum iron level was evaluated by using commercial kits. RESULTS AND

conclusionAccording to CFU measurements, after 96 hours, mice can clear MSR-1 from their body with different routes of injection. We have also shown that MSR-1 bacteria can affect the blood iron level in mice. The serum iron level decreased from control level in the first 24 h after i.v injection (P< 0.05). Our research on optimizing the biological magnetic system is still continuing.

Indexed as

Magnetospirillum gryphiswaldenseMiceSerum Iron Level

Identifiers

PMID23066493

PMCPMC3465544

OpenAlexW2100449537

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.