ArticleAfrican health sciences2012
Hepatitis C virus (HCV) status in newborns born to HCV positive women performing intracytoplasmic sperm injection.
Article in African health sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Investigating Oxidative Stress Levels in Pregnant Patients Infected with Hepatitis C Virus and Bacterial Vaginosis for Better Treatment Option.Oman medical journal · 2023Article
- ESHRE guideline: medically assisted reproduction in patients with a viral infection/disease.Human reproduction open · 2021Article
- Hepatitis C Virus Infection in Children and Pregnant Women: An Updated Review of the Literature on Screening and Treatments.AJP reports · 2020Article
- Effect of hepatitis C virus infection on the outcomes of in vitro fertilization.International journal of clinical and experimental medicine · 2015Article
- Back to our roots: infections, HIV and maternal mortality in Africa.African health sciences · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA low risk of HCV vertical transmission has been reported especially in those born to women with viraemia. Intracytoplasmic sperm injection (ICSI) being an assisted reproduction technique includes procedures that may increase risk of transmission.
objectiveTo determine the rate of vertical transmission of HCV to newborns born to HCV positive mothers in ICSI cycles.
methodsIn a cross-sectional observational study, serum samples have were collected within the first week after birth from newborns of two groups of ICSI cycles females. Group one: 30 women HCV antibody (Ab) positive/HCV RNA negative. Group two: 30 women HCV Ab positive/HCV RNA positive. Newborn sera were subjected to HCV antibody testing, and detection of HCV viral RNA by PCR.
resultsNone of the newborns born to PCR negative females undergoing ICSI cycles showed positive results neither for HCV antibody, or for HCV RNA. Only one out of the 30 newborns born to PCR positive females was positive for HCV antibody and HCV RNA.
conclusionHCV vertical transmission in ICSI cycles seemed to be of low incidence in PCR positive women, while in the case of HCV PCR negative/sero-positive women, it appeared to be completely absent. This observation could have an impact on the clinicians' counseling for HCV positive females seeking ICSI.
Indexed as
Identifiers
23066421PMC3462519W1745101701What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.