Evidence map›Paper›PMID 23066352›Full record

ArticleIEEE sensors journal2012

High Throughput Micropatterning of Optical Oxygen Sensor for Single Cell Analysis.

Haixin Zhu, Yanqing Tian, Shivani Bhushan, Fengyu Su, Deirdre R Meldrum

Abstract read
In one paragraph

Article in IEEE sensors journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Haixin ZhuCenter for Biosignatures Discovery Automation, The Biodesign Institute at Arizona State University, Tempe, AZ 85287.
Yanqing Tian
Shivani Bhushan
Fengyu Su
Deirdre R Meldrum
Arizona State University · USIntel (United States) · US

Funding

CEGSTech: Integrated Biologically-Active MicrosystemsP50HG002360 · NHGRI · UNIVERSITY OF WASHINGTON · PI MELDRUM, DEIRDRE R. · 2001 to 2012
$37.8M
NHGRI NIH HHS P50 HG002360
6 · The paper itself

Abstract

In this paper, we present our results from process development and characterization of optical oxygen sensors that are patterned by traditional UV lithography. An oxygen sensitive luminescent probe, platinum octaethylporphyrin (PtOEP), was encapsulated in commercially purchased photoresist (AZ5214) to form uniform thin sensor films on fused silica substrates. Plasticizer ethoxylated trimethylolpropane triacrylate (SR454) was added to the dye-photoresist sensor mixtures to improve the oxygen sensitivity. The optimum sensor mixture composition that can be patterned with maximum sensitivity was identified. The microfabrication process conditions, cell adherence and oxygen sensitivity results from patterned structures were characterized in detail. Down to 3 µm features have been fabricated on fused silica substrates using the developed techniques. The result implies the developed methods can provide a feasible way to miniaturize the optical sensor system for single cell analysis with precise control of sensor volume and response.

Identifiers

PMID23066352
PMCPMC3468159
OpenAlexW1964042643

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.