Evidence map›Paper›PMID 23066330›Full record

ArticleWorld journal of gastroenterology2012

Penicillium marneffei chylous ascites in acquired immune deficiency syndrome: a case report.

Yin-Zhong Shen, Zhen-Yan Wang, Hong-Zhou Lu

Open access · greenAbstract readCase Reports
In one paragraph

Article in World journal of gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yin-Zhong ShenDepartment of Infectious Diseases, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Zhen-Yan Wang
Hong-Zhou Lu
Shanghai Public Health Clinical Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Penicillium marneffei (P. marneffei) infection usually occurs with skin, bone marrow, lung or hepatic involvement. However, no cases of P. marneffei infection with chylous ascites have been reported thus far. In this report, we describe the first case of acquired immune deficiency syndrome (AIDS) which has been complicated by a P. marneffei infection causing chylous ascites. We describe the details of the case, with an emphasis on treatment regimen. This patient was treated with amphotericin B for 3 mo, while receiving concomitant therapy with an efavirenz-containing antiretroviral regimen, but cultures in ascitic fluid were persistently positive for P. marneffei. The infection resolved after treatment with high-dose voriconazole (400 mg every 12 h) for 3 mo. P. marneffei should be considered in the differential diagnosis of chylous ascites in human immunodeficiency virus patients. High-dose voriconazole is an effective, well-tolerated and convenient option for the treatment of systemic infections with P. marneffei in AIDS patients on an efavirenz-containing antiretroviral regimen.

Indexed as

Acquired Immunodeficiency SyndromeAIDS-Related Opportunistic InfectionsAlkynesAmphotericin BAntifungal AgentsAnti-Retroviral AgentsBenzoxazinesChylous AscitesCyclopropanesDiagnosis, DifferentialHumansMaleMiddle AgedMycosesPenicilliumPyrimidinesAlkynesAmphotericin BAntifungal AgentsAnti-Retroviral AgentsBenzoxazinesCyclopropanesefavirenzPyrimidinesTriazolesVoriconazoleAcquired immune deficiency syndromeChylous ascitesEfavirenzFungal sepsisPenicillium marneffeiVoriconazole

Identifiers

PMID23066330
PMCPMC3468868
OpenAlexW1901716865

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.