Evidence map›Paper›PMID 23065771›Full record

ReviewNMR in biomedicine2013

Multimodal iron oxide nanoparticles for hybrid biomedical imaging.

Timo Heidt, Matthias Nahrendorf

Abstract readReview
In one paragraph

Review in NMR in biomedicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Imaging and nanomedicine in inflammatory atherosclerosis.Science translational medicine · 2014
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Timo HeidtCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Matthias Nahrendorf

Funding

PET/MRI of cardiac repairR01HL096576 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NAHRENDORF, MATTHIAS · 2009 to 2017
$2.8M
Imaging of Cardiac Transplant RejectionR01HL095629 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NAHRENDORF, MATTHIAS · 2009 to 2013
$2.2M
NHLBI NIH HHS HHSN268201000044CNHLBI NIH HHS R01 HL095629NHLBI NIH HHS R01HL095629NHLBI NIH HHS R01 HL096576NHLBI NIH HHS R01HL096576
6 · The paper itself

Abstract

Iron oxide core nanoparticles are attractive imaging agents because their material properties allow the tuning of pharmacokinetics as well as the attachment of multiple moieties to their surface. In addition to affinity ligands, these include fluorochromes and radioisotopes for detection with optical and nuclear imaging. As the iron oxide core can be detected by MRI, options for combining imaging modalities are manifold. Already, preclinical imaging strategies have combined noninvasive imaging with higher resolution techniques, such as intravital microscopy, to gain unprecedented insight into steady-state biology and disease. Going forward, hybrid iron oxide nanoparticles will help to merge modalities, creating a synergy that will enable imaging in basic research and, potentially, also in the clinic.

Indexed as

Ferric CompoundsMultimodal ImagingNanoparticlesAnimalsAtherosclerosisClinical Trials as TopicHumansMagnetic Resonance ImagingFerric Compoundsferric oxide

Identifiers

PMID23065771
PMCPMC3549036

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.