Evidence map›Paper›PMID 23065733›Full record

ArticleAnnals of the rheumatic diseases2013

Demographic and disease-related predictors of abnormal lung function in patients with established inflammatory polyarthritis and a comparison with the general population.

Suzanne M M Verstappen, Mark Lunt, Robert N Luben, Jackie Chipping, Tarnya Marshall, Kay-Tee Khaw, Nick Wareham, William G Dixon, Ian N Bruce, Deborah P M Symmons

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Annals of the rheumatic diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Suzanne M M VerstappenArthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK. Suzanne.Verstappen@manchester.ac.uk
Mark Lunt
Robert N Luben
Jackie Chipping
Tarnya Marshall
Kay-Tee Khaw
Nick Wareham
William G Dixon
Ian N Bruce
Deborah P M Symmons
University of Manchester · GBUniversity of Cambridge · GBNorfolk and Norwich University Hospital · GBNIHR Oxford Musculoskeletal Biomedical Research Centre · GB

Funding

Arthritis Research UK 20380Department of Health MANMKBRU-2012-1Medical Research Council G0401527Medical Research Council G0902272Medical Research Council G1000143Medical Research Council MC_U106179471Medical Research Council MC_UU_12015/1
6 · The paper itself

Abstract

objectivesTo identify demographic and clinical predictors of obstructive lung disease (OLD) and restrictive lung disease (RLD) in patients with established inflammatory polyarthritis (IP) and to compare the prevalence of respiratory symptoms in patients with IP and the general population.

methodA total of 421 patients with IP underwent a spirometry test 15 years after inclusion in the Norfolk Arthritis Register (NOAR). Logistic regression analyses were performed to assess the predictive ability of demographic and clinical characteristics obtained at inclusion in NOAR and to assess their association with OLD or RLD at 15 years (age- and gender-adjusted). In addition, the prevalence of OLD and RLD was compared with a matched population (1:4) of people participating in the European Prospective Investigation of Cancer-Norfolk, a representative sample of the general population in Norfolk, UK.

resultsIn this IP population, current smoking was the strongest predictor for OLD and functional disability for RLD. In the comparison study, 11.6% had OLD in the IP population and 4.9% in the general population (adjOR 2.01, 95% CI 1.26 to 3.22). The prevalence of RLD was not statistically different between the IP population and the general population (14.6% vs 17.5%; adjOR 0.76, 95% CI 0.53 to 1.10).

conclusionsOLD, but not RLD, is more prevalent in the IP population than in the general population. Functional disability is especially associated with RLD whereas smoking is associated with OLD. The latter finding, and the known association between smoking and a poor disease prognosis, underlines the importance of smoking cessation in patients with IP.

Indexed as

AdultAgedAged, 80 and overArthritisComorbidityDemographyFemaleHumansLungLung Diseases, ObstructiveMaleMiddle AgedPredictive Value of TestsPrevalenceRegistriesRespiratory Function TestsArthritisEpidemiologyOutcomes research

Identifiers

PMID23065733
PMCPMC3756524
OpenAlexW2140539157

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.