ReviewElectrophoresis2012
Microfluidic transport in microdevices for rare cell capture.
Review in Electrophoresis, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Single-cell Technology in Stem Cell Research.Current stem cell research & therapy · 2025Review
- Microscale Flow Control and Droplet Generation Using Arduino-Based Pneumatically-Controlled Microfluidic Device.Biosensors · 2024Article
- Effective Boundary Correction for Deterministic Lateral Displacement Microchannels to Improve Cell Separation: A Numerical and Experimental Study.Biosensors · 2024Article
- The Impact of Injection Distance to Bifurcations on Yttrium-90 Distribution in Liver Cancer Radioembolization.Journal of vascular and interventional radiology : JVIR · 2022Article
- Microfluidics as efficient technology for the isolation and characterization of stem cells.EXCLI journal · 2021Review
- Recent advances in microfluidic methods in cancer liquid biopsy.Biomicrofluidics · 2019Review
- On-chip pressure generation using a gel membrane fabricated outside of the microfluidic network.Electrophoresis · 2019Article
- A High Aspect Ratio Bifurcated 128-Microchannel Microfluidic Device for Environmental Monitoring of Explosives.Sensors (Basel, Switzerland) · 2018Article
- Selective Adhesive Cell Capture without Molecular Specificity: New Surfaces Exploiting Nanoscopic Polycationic Features as Discrete Adhesive Units.RSC advances · 2017Article
- Diffusion phenomena of cells and biomolecules in microfluidic devices.Biomicrofluidics · 2015Article
- Microfluidic isolation of cancer-cell-derived microvesicles from hetergeneous extracellular shed vesicle populations.Biomedical microdevices · 2014Article
- Characterization of microfluidic shear-dependent epithelial cell adhesion molecule immunocapture and enrichment of pancreatic cancer cells from blood cells with dielectrophoresis.Biomicrofluidics · 2014Article
- Rare cell isolation and analysis in microfluidics.Lab on a chip · 2014Review
- Parametric control of collision rates and capture rates in geometrically enhanced differential immunocapture (GEDI) microfluidic devices for rare cell capture.Biomedical microdevices · 2014Article
- Discontinuous nanoporous membranes reduce non-specific fouling for immunoaffinity cell capture.Small (Weinheim an der Bergstrasse, Germany) · 2013Article
- Enrichment of prostate cancer cells from blood cells with a hybrid dielectrophoresis and immunocapture microfluidic system.Biomedical microdevices · 2013Article
- Characterization of a hybrid dielectrophoresis and immunocapture microfluidic system for cancer cell capture.Electrophoresis · 2013Article
- Microfluidic enrichment of mouse epidermal stem cells and validation of stem cell proliferation in vitro.Tissue engineering. Part C, Methods · 2013Article
- Stem Cell Separation Technologies.Current opinion in chemical engineering · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The isolation and capture of rare cells is a problem uniquely suited to microfluidic devices, in which geometries on the cellular length scale can be engineered and a wide range of chemical functionalizations can be implemented. The performance of such devices is primarily affected by the chemical interaction between the cell and the capture surface and the mechanics of cell-surface collision and adhesion. As rare cell-capture technology has been summarized elsewhere (E. D. Pratt et al., Chem. Eng. Sci. 2011, 66, 1508-1522), this article focuses on the fundamental adhesion and transport mechanisms in rare cell-capture microdevices, and explores modern device design strategies in a transport context. The biorheology and engineering parameters of cell adhesion are defined; adhesion models and reaction kinetics briefly reviewed. Transport at the microscale, including diffusion and steric interactions that result in cell motion across streamlines, is discussed. The review concludes by discussing design strategies with a focus on leveraging the underlying transport phenomena to maximize device performance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.