ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2013
Usefulness of contrast-enhanced intraoperative ultrasonography (CE-IOUS) in patients with colorectal liver metastases after preoperative chemotherapy.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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15 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- A meta-analysis evaluating contrast-enhanced intraoperative ultrasound (CE-IOUS) in the context of surgery for colorectal liver metastases.Abdominal radiology (New York) · 2021Pooled it
- Review
- Intraoperative hepatic ultrasonography in patients with gastrointestinal and pancreatic neuroendocrine neoplasms without preoperative evidence of liver metastases.Journal of neuroendocrinology · 2025Article
- Improved sensitivity and positive predictive value of contrast-enhanced intraoperative ultrasound in colorectal cancer liver metastasis: a systematic review and meta-analysis.Journal of gastrointestinal oncology · 2022Article
- Current role of intraoperative ultrasonography in hepatectomy.Surgery today · 2021Review
- Colorectal liver metastases: Current management and future perspectives.World journal of clinical oncology · 2020Review
- [Intraoperative ultrasound in visceral surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020Review
- Parenchymal-sparing liver surgery in patients with colorectal carcinoma liver metastases.World journal of gastrointestinal surgery · 2016Review
- Augmented Reality Guidance for the Resection of Missing Colorectal Liver Metastases: An Initial Experience.World journal of surgery · 2016Article
- Intraoperative Contrast-Enhanced Ultrasound in Colorectal Liver Metastasis Surgery Improves the Identification and Characterization of Nodules.World journal of surgery · 2016Article
- Disappearing liver metastases from colorectal cancer: impact of modern imaging modalities.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2015Article
- The role of intraoperative ultrasonography in the diagnosis and management of focal hepatic lesions.Ultrasonography (Seoul, Korea) · 2015Review
- Is intraoperative ultrasound still useful for the detection of colorectal cancer liver metastases?HPB : the official journal of the International Hepato Pancreato Biliary Association · 2015Article
- The Most Appropriate Time Delay after Microbubble Contrast Agent Intravenous Injection to Maximize Liver Metastasis Conspicuity on Contrast-Enhanced Ultrasound.Journal of medical ultrasoundArticle
- Update on the role of imaging in management of metastatic colorectal cancer.Radiographics : a review publication of the Radiological Society of North America, IncReview
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9 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
aimsThe aim of this study was to evaluate the ability of contrast-enhanced intraoperative ultrasonography to detect colorectal liver metastases after preoperative chemotherapy compared with intraoperative ultrasound and preoperative imaging techniques.
methodsFrom January 2010 to December 2011, 28 patients with colorectal liver metastases underwent intraoperative ultrasonography and contrast-enhanced intraoperative ultrasonography during hepatectomy following preoperative chemotherapy. The findings were compared to preoperative imaging using contrast-enhanced ultrasonography, computed tomography, magnetic resonance imaging, and/or fluorodeoxyglucose positron emission tomography.
resultsPreoperative imaging techniques detected 58 metastatic lesions in 28 patients. In 32 % of patients (n = 9), intraoperative ultrasound detected 24 missed hepatic nodules. In 14 % of patients (n = 4), contrast-enhanced intraoperative ultrasonography detected an additional six nodules and change in operative management occurred in 18 % of patients. Using univariate analysis, we found three factors significantly related to detection of additional metastases with contrast-enhanced intraoperative ultrasonography: three or more metastases before chemotherapy (p = 0.047), resolution of at least one metastasis (p = 0.011), and small liver metastases (largest lesion size ≤20 mm) after chemotherapy (p = 0.007).
conclusionIn patients undergoing surgery for colorectal liver metastases after chemotherapy, contrast-enhanced intraoperative ultrasonography improved both the sensitivity of intraoperative ultrasonography to detect liver metastases and the R0 hepatic resection rate.
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