ArticleVeterinary research communications2013
Intracerebroventricular injection of ghrelin produces hypophagia through central serotonergic mechanisms in chicken.
Article in Veterinary research communications, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 36 citations in OpenAlex.
- Article
- Effects of central injection of liver-expressed antimicrobial peptide-2 (LEAP2) on feed intake in broiler chickens: interactions with opioidergic and serotonergic systems.Veterinary research communications · 2025Article
- Decoding the role of ghrelin and its interactions with central signaling pathways in avian appetite regulation.Veterinary research communications · 2025Review
- Mediatory role of the dopaminergic system through D1 receptor on glycine-induced hypophagia in neonatal broiler-type chickens.Amino acids · 2021Article
- Neuropeptide Control of Feeding Behavior in Birds and Its Difference with Mammals.Frontiers in neuroscience · 2016Review
- Modulation of opioid-induced feeding behavior by endogenous nitric oxide in neonatal layer-type chicks.Veterinary research communications · 2015Article
- Role of cannabinoidergic system on food intake in neonatal layer-type chicken.Veterinary research communications · 2015Article
- Ghrelin-induced hypophagia is mediated by the β2 adrenergic receptor in chicken.The journal of physiological sciences : JPS · 2014Article
- Dopamine-induced hypophagia is mediated by D1 and 5HT-2c receptors in chicken.Veterinary research communications · 2014Article
- The effect of serotonergic system on nociceptin/orphanin FQ induced food intake in chicken.The journal of physiological sciences : JPS · 2013Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been stated that central injection of ghrelin is acting as an anorexigenic peptide in chicken. Ghrelin activity was studied through some neuronal pathways. The present study was designed in 4 experiments to examine the hypophagic response of ghrelin through the central serotonergic system in chicken. The guide cannula was surgically implanted in the right lateral ventricle of the chickens. In experiment 1, intacerebroventricular injection with PCPA (1.5 mg) performed followed by ghrelin (0.6 nmol). In experiments 2, 3 and 4 prior to ghrelin injection, chickens received fluoxetine (10 μg), 8-OH-DPAT (15.25 nmol), SB242084 (1.5 μg) respectively via guide cannula intacerebroventricularly. Cumulative food intake was determined at 3 h post injection. The results of this study showed that flouxetine pretreatment significantly amplified ghrelin hypophagia in chicken (p < 0.05). The hypophagic effect of ghrelin was attenuated by pretreatment with PCPA and SB242084 (p < 0.05) but 8-OH-DPAT had no effect. These results suggest that hypophagic effect of ghrelin probably is mediated by serotonergic mechanisms via 5-HT(2C) receptor.
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