ReviewJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2012
What is the role of calcium scoring in the age of coronary computed tomographic angiography?
Review in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 24 citations in OpenAlex.
- Staged testing as a solution to the challenges of testing lower risk patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Imaging Cardiovascular Calcification.Journal of the American Heart Association · 2018Review
- Calcifying Matrix Vesicles and Atherosclerosis.BioMed research international · 2017Review
- Technical feasibility and validation of a coronary artery calcium scoring system using CT coronary angiography images.European radiology · 2016Article
- Deriving coronary artery calcium scores from CT coronary angiography: a proposed algorithm for evaluating stable chest pain.The international journal of cardiovascular imaging · 2014Article
- Has our understanding of calcification in human coronary atherosclerosis progressed?Arteriosclerosis, thrombosis, and vascular biology · 2014Review
- Incremental prognostic value of coronary artery calcium score versus CT angiography among symptomatic patients without known coronary artery disease.Atherosclerosis · 2014Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-contrast-enhanced CT for coronary artery calcification (CAC) as a marker of coronary atherosclerosis has been studied extensively in the primary prevention setting. With rapidly evolving multidetector CT technology, contrast-enhanced coronary CT angiography (CCTA) has emerged as the non-invasive method of choice for detailed imaging of the coronary tree. In this review, we systematically evaluate the role of CAC testing in the age of CCTA in both asymptomatic and symptomatic patients, across varying levels of risk. Although the role of CAC testing is well established in asymptomatic subjects, its use in evaluating those with stable symptoms that represent possible obstructive coronary artery disease is controversial. Nevertheless, available data suggest that in low-to-intermediate risk symptomatic patients, CAC scanning may serve as an appropriate gatekeeper to further testing with either CCTA (if no or only mild CAC present) versus functional imaging or invasive coronary angiography (when moderate or severe CAC present). Given the strong short-term prognostic value of CAC = 0, studies are needed to further evaluate the role of CAC scanning in low-risk patients with acute chest pain presenting to the emergency room.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.