Evidence map›Paper›PMID 23065370›Full record

ReviewCurrent diabetes reports2013

Impact of hypoglycemia in hospitalized patients.

Michelle Carey, Laura Boucai, Joel Zonszein

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current diabetes reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03006510 (Leveraging the Power of the EMR), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03006510 nacompletednot on this mapstarted 2017, after this paper: background citation

Leveraging the Power of the EMR: Using a Real Time Prediction Model to Decrease Inpatient Hypoglycemic Events

TypeinterventionalSponsorUniversity of California, San FranciscoRan2017 to 2018Enrolled498ConditionsHypoglycemiaArmsHypoglycemia prediction alert
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Association of Hypoglycemia With the Time to Dextrose in Treatment of Diabetes-Related Ketoacidosis.Clinical diabetes : a publication of the American Diabetes Association · 2025
    Article
  8. Medications that Regulate Gastrointestinal Transit Influence Inpatient Blood Glucose.medRxiv : the preprint server for health sciences · 2024
    Article
  9. Tigecycline and Hypoglycemia, When and How?The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2024
    Review
  10. Review
  11. Risk Factors for Inpatient Hypoglycemia in a Tertiary Care Hospital in Indonesia.Journal of the ASEAN Federation of Endocrine Societies · 2022
    Article
  12. Hypoglycemia symptoms are reduced in hospitalized patients with diabetes.Journal of diabetes and its complications · 2021
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Interventions to Improve Adherence to a Hypoglycemia Protocol.Diabetes spectrum : a publication of the American Diabetes Association · 2017
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michelle CareyDepartment of Medicine, Division of Endocrinology and Metabolism, Montefiore Medical Center, the University Hospital for Albert Einstein College of Medicine, 1825 Eastchester Road, Bronx, NY 10461, USA, mcarey@montefiore.org
Laura Boucai
Joel Zonszein

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoglycemia is a common problem in hospitalized patients, particularly the elderly, frail, and severely ill. Hypoglycemia has been implicated in the development of adverse clinical outcomes, including increased mortality. Fear of iatrogenic hypoglycemia remains an obstacle to adequate inpatient glycemic control. However, evidence from large clinical trials is mixed: several intensive care unit studies have shown either reduced or no change in mortality with intensive glycemic control, despite high rates of iatrogenic hypoglycemia, and only 1 large study showed higher mortality. In the general ward setting, the association of hypoglycemia with worse outcomes and mortality has been frequently reported, but after multivariate adjustment for comorbidities this association disappears. Spontaneous hypoglycemia, rather than iatrogenic hypoglycemia, is strongly associated with mortality suggesting that hypoglycemia behaves as a biomarker rather than a causative factor of adverse outcomes. Inpatient glycemic management should be patient-centered, follow the current guidelines, and aimed at preventing hypoglycemia.

Indexed as

HospitalizationBlood GlucoseHumansHypoglycemiaInpatientsPatient CareRisk FactorsBlood Glucose

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.