Evidence map›Paper›PMID 23065264›Full record

ReviewMolecular biology reports2012

Cathelicidins: family of antimicrobial peptides. A review.

Ewa M Kościuczuk, Paweł Lisowski, Justyna Jarczak, Nina Strzałkowska, Artur Jóźwik, Jarosław Horbańczuk, Józef Krzyżewski, Lech Zwierzchowski, Emilia Bagnicka

Open access · hybridAbstract readReview
In one paragraph

Review in Molecular biology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 292 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
292citing papers in PubMed, 2 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

292 citing papers in PubMed, 2 syntheses or guidelines pooled it, 559 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Macroscopic Markers of Dolphin Healing at Sea Linked to Immunity.Animals : an open access journal from MDPI · 2026
    Article
  12. Article
  13. Review
  14. Proteomic Analysis of Influenza.Advances in experimental medicine and biology · 2026
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Post-burn Lung Inflammation Is Associated With Induction of Pulmonary Cathelicidin-related Antimicrobial Peptide and S100a8 in Mice.Journal of burn care & research : official publication of the American Burn Association · 2025
    Article
  20. Review

232 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ewa M KościuczukInstitute of Genetics and Animal Breeding in Jastrzębiec, Polish Academy of Sciences, 05-552, Magdalenka, Poland.
Paweł Lisowski
Justyna Jarczak
Nina Strzałkowska
Artur Jóźwik
Jarosław Horbańczuk
Józef Krzyżewski
Lech Zwierzchowski
Emilia Bagnicka
Polish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cathelicidins are small, cationic, antimicrobial peptides found in humans and other species, including farm animals (cattle, horses, pigs, sheep, goats, chickens, rabbits and in some species of fish). These proteolytically activated peptides are part of the innate immune system of many vertebrates. These peptides show a broad spectrum of antimicrobial activity against bacteria, enveloped viruses and fungi. Apart from exerting direct antimicrobial effects, cathelicidins can also trigger specific defense responses in the host. Their roles in various pathophysiological conditions have been studied in mice and humans, but there are limited information about their expression sites and activities in livestock. The aim of the present review is to summarize current information about these antimicrobial peptides in farm animals, highlighting peptide expression sites, activities, and future applications for human and veterinary medicine.

Indexed as

Amino Acid SequenceAnimalsCathelicidinsGenetic VariationHumansMolecular Sequence DataCathelicidins

Identifiers

PMID23065264
PMCPMC3487008
OpenAlexW2041942794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.