ArticleMolecular biology reports2013
RAD51 polymorphisms and breast cancer risk.
Article in Molecular biology reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- RAD51 135G>C substitution increases breast cancer risk in an ethnic-specific manner: a meta-analysis on 21,236 cases and 19,407 controls.Scientific reports · 2015Pooled it
- Modification ofInternational journal of environmental research and public health · 2020Article
- Expression of RAD51 and Its Clinical Impact in Oral Squamous Cell Carcinoma.Analytical cellular pathology (Amsterdam) · 2020Article
- Polymorphism of DNA repair genes in breast cancer.Oncotarget · 2019Article
- New single nucleotide polymorphisms (SNPs) in homologous recombination repair genes detected by microarray analysis in Polish breast cancer patients.Clinical and experimental medicine · 2017Article
- Polymorphisms in RAD51 and their relation with breast cancer in Saudi females.OncoTargets and therapy · 2016Article
- Single Nucleotide Polymorphisms (SNPs) of RAD51-G172T and XRCC2-41657C/T Homologous Recombination Repair Genes and the Risk of Triple- Negative Breast Cancer in Polish Women.Pathology oncology research : POR · 2015Article
- Evaluation of miRNA-binding-site SNPs of MRE11A, NBS1, RAD51 and RAD52 involved in HRR pathway genes and risk of breast cancer in China.Molecular genetics and genomics : MGG · 2015Article
- Association between single nucleotide polymorphisms (SNPs) of XRCC2 and XRCC3 homologous recombination repair genes and triple-negative breast cancer in Polish women.Clinical and experimental medicine · 2015Article
- Association between RAD51 polymorphism and breast cancer susceptibility: a meta analysis.International journal of clinical and experimental medicine · 2015Article
- Association of polymorphisms in the 5' untranslated region of RAD51 gene with risk of endometrial cancer in the Polish population.Archives of gynecology and obstetrics · 2014Article
- Haplotype analyses of DNA repair gene polymorphisms and their role in ulcerative colitis.PloS one · 2014Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer (BC) is one of the most common causes of death among women, and second in Iran. The objectives of this study were to determine the frequency of RAD51 G/C polymorphism in patients with breast cancer. We evaluated these polymorphisms and effects on the breast cancer risk association in a Iranian sporadic population-based case-control study of 294 breast cancer cases and 315 controls using a PCR-RFLP-based assay. Analyses of affected and controls show that homozygote genotype RAD51 GG has the highest frequency in both groups (33.3 in patients and 41.4 in control group). Genotype RAD51 GG most risk factor were in our population: [CC/GC odds ratio, 0.364 (95 % confidence interval; CI, 0.168-0.788) p = 0.009, CC/GG odds ratio, 0.828 (95 % CI, 0.411-1.668) p = 0.596], GG/GC odds ratio, 2.276 (95 % CI, 1.497-3.460) p = 0.001]. There was a significant association of breast cancer risk with RAD51 GG and CC polymorphism.
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