SynthesisJournal of assisted reproduction and genetics2012
Follicular flushing during oocyte retrieval: a systematic review and meta-analysis.
Synthesis in Journal of assisted reproduction and genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Follicle Flushing on Oocyte Fertilization Rate
Oocyte Recovery Rate Following Follicular Flushing Versus Direct Aspiration in Women Undergoing IVF
Does Addition of Follicular Flushing to the Initial Aspiration Lead to Higher Numbers of Oocytes Retrieved in Women Undergoing Oocyte Retrieval? A Randomized Controlled Trial
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Follicular flushing during oocyte retrieval in assisted reproductive techniques.The Cochrane database of systematic reviews · 2022Pooled it
- Follicular flushing during oocyte retrieval in assisted reproductive techniques.The Cochrane database of systematic reviews · 2018Pooled it
- Evaluation of follicular flushing with double lumen needle in patients undergoing assisted reproductive technology treatments.JBRA assisted reproduction · 2021Trial
- Follicular flushing leads to higher oocyte yield in monofollicular IVF: a randomized controlled trial.Human reproduction (Oxford, England) · 2020Trial
- Impact of Systematic Follicular Flushing on Egg Retrieval and Embryo Quality in IVF-ICSI Cycles: A Controlled Study?Journal of clinical medicine · 2025Article
- Single or Double-Lumen Aspiration Needle? Revisiting Choices for In Vitro Fertilization or Intracytoplasmic Sperm Injection-A Critical Review.Life (Basel, Switzerland) · 2025Review
- Causes and Effects of Oocyte Retrieval Difficulties: A Retrospective Study of 10,624 Cycles.Frontiers in endocrinology · 2021Article
- Follicular flushing increases the number of oocytes retrieved in poor ovarian responders undergoing in vitro fertilization: a retrospective cohort study.BMC women's health · 2018Article
- Effect of follicular flushing on reproductive outcomes in patients with poor ovarian response undergoing assisted reproductive technology.Journal of assisted reproduction and genetics · 2017Article
- Approaches to oocyte retrieval for advanced reproductive technology cycles planning to utilize in vitro maturation: a review of the many choices to be made.Journal of assisted reproduction and genetics · 2014Review
- Oocyte retrieval at 140-mmHg negative aspiration pressure: A promising alternative to flushing and aspiration in assisted reproduction in women with low ovarian reserve.Journal of human reproductive sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this systematic review and meta-analysis was to examine the literature and identify randomized controlled trials (RCTs), in order to answer if performing follicular flushing during the oocyte retrieval may improve the assisted reproductive technologies (ART) outcomes.
methodsAn exhaustive electronic search was performed using MEDLINE and EMBASE databases. Only RCTs comparing follicular flushing to aspiration only during ART, were included. We included 5 trials, with a total of 482 patients randomized, with median ages ranging from 30.5 to 37.1.
resultsThe data analyses did not show significant differences regarding live birth rate, clinical pregnancies rates, and the number of oocytes retrieved. The duration of oocyte retrieval was significantly increased in the follicular flushing group.
conclusionsThe results from this systematic review and meta-analysis suggest that there is no advantage to use of routine follicular flushing during OR in an unselected group of patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.