Evidence map›Paper›PMID 23064818›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2013

Health consequences of familial longevity influence among the Chinese elderly.

Yi Zeng, Huashuai Chen, Xiaoming Shi, Zhaoxue Yin, Ze Yang, Jun Gu, Dan Blazer

Abstract readComparative Study
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yi ZengCenter for Study of Aging and Human Development, School of Medicine, Duke University, PO Box 3003, Durham, NC 27710, USA. zengyi68@gmail.com
Huashuai Chen
Xiaoming Shi
Zhaoxue Yin
Ze Yang
Jun Gu
Dan Blazer

Funding

Demographic Analysis on Determinants of Healthy Longevity in ChinaR01AG023627 · NIA · DUKE UNIVERSITY · PI ZENG, YI · 2004 to 2014
$3.9M
NIA NIH HHS R01 AG023627
6 · The paper itself

Abstract

backgroundA comparative analysis between centenarians' children and neighborhood controls is an efficient approach to learn how familial longevity influence and its interaction with environmental factors affect healthy aging. Yet, there are few extant studies that inform this topic; this study expands this literature.

methodsWe analyze data from 417 children of centenarians and 560 neighborhood controls without family history of longevity in China (all participants aged 60-80) using ordered logit regression models.

resultsWe found that, compared to the neighborhood controls and adjusted for various potentially confounding factors, centenarians' children had significantly better instrumental activities of daily living function(p < .001), smaller number of chronic conditions or health problems(p < .01), less anxiety and loneliness(p < .01), better cognitive function (p < .01), more resilience (p < .01), better self-rated health (p < .001), and better self-rated life satisfaction (p < .001). The results also reveal that interactions between familial longevity influence and one of three environmental factors (whether, as children, they received adequate medical care when ill, number of living children, and household economic conditions) may possibly affect health outcomes at old ages (p < .05). We discovered that effects of the environmental factors on health outcome are substantially stronger among elders who have no family history of longevity compared to centenarians' children who probably carry positive genes and/or lifestyle behaviors from their long-lived parent(s), which may promote longevity.

conclusionFamilial longevity influence, through genetics and family lifestyle, is significantly associated with various aspects of health at older ages. Interactions between familial longevity influence and some environmental factors may affect health in old age.

Indexed as

AgingEnvironmentSocial EnvironmentAdult ChildrenAgedAged, 80 and overAsian PeopleChinaCohort EffectConfounding Factors, EpidemiologicFamily HealthFemaleGeriatric AssessmentHealth Status IndicatorsHumansIntelligence Tests

Identifiers

PMID23064818
PMCPMC3593617

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.