Evidence map›Paper›PMID 23064704›Full record

ReviewCellular and molecular life sciences : CMLS2013

Intrinsic control of mammalian retinogenesis.

Mengqing Xiang

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

  1. Article
  2. Foxn3 is required to suppress aberrant ciliogenesis in nonphotoreceptor retinal neurons.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  16. Review
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Mengqing XiangCenter for Advanced Biotechnology and Medicine, Rutgers University, 679 Hoes Lane West, Piscataway, NJ, 08854, USA. xiang@cabm.rutgers.edu

Funding

Transcriptional Regulation of Retinal DevelopmentR01EY012020 · NEI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI XIANG, MENGQING · 1998 to 2012
$3.7M
Dll4 Gene Regulation and Function during RetinogenesisR01EY020849 · NEI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI XIANG, MENGQING · 2010 to 2013
$1.5M
NEI NIH HHS EY012020NEI NIH HHS EY020849NEI NIH HHS R01 EY012020NEI NIH HHS R01 EY020849
6 · The paper itself

Abstract

The generation of appropriate and diverse neuronal and glial types and subtypes during development constitutes the critical first step toward assembling functional neural circuits. During mammalian retinogenesis, all seven neuronal and glial cell types present in the adult retina are specified from multipotent progenitors by the combined action of various intrinsic and extrinsic factors. Tremendous progress has been made over the past two decades in uncovering the complex molecular mechanisms that control retinal cell diversification. Molecular genetic studies coupled with bioinformatic approaches have identified numerous transcription factors and cofactors as major intrinsic regulators leading to the establishment of progenitor multipotency and eventual differentiation of various retinal cell types and subtypes. More recently, non-coding RNAs have emerged as another class of intrinsic factors involved in generating retinal cell diversity. These intrinsic regulatory factors are found to act in different developmental processes to establish progenitor multipotency, define progenitor competence, determine cell fates, and/or specify cell types and subtypes.

Indexed as

AnimalsCell DifferentiationForkhead Transcription FactorsIntracellular Signaling Peptides and ProteinsMembrane ProteinsReceptors, NotchRetinaRetinal Ganglion CellsRNA, UntranslatedSignal TransductionStem CellsTranscription Factorsdelta proteinForkhead Transcription FactorsIntracellular Signaling Peptides and ProteinsMembrane ProteinsReceptors, NotchRNA, UntranslatedTranscription Factors

Identifiers

PMID23064704
PMCPMC3566347

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.