ArticleSexually transmitted diseases2012
Rates and determinants of oral human papillomavirus infection in young men.
Article in Sexually transmitted diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.
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Who cites it
56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 117 citations in OpenAlex.
- The incidence, clearance and persistence of non-cervical human papillomavirus infections: a systematic review of the literature.BMC infectious diseases · 2016Pooled it
- The use of web-based diaries in sexual risk behaviour research: a systematic review.Sexually transmitted infections · 2014Pooled it
- Multisite HPV16/18 Vaccine Efficacy Against Cervical, Anal, and Oral HPV Infection.Journal of the National Cancer Institute · 2016Trial
- Alcohol and Tobacco Increases Risk of High Risk HPV Infection in Head and Neck Cancer Patients: Study from North-East Region of India.PloS one · 2015Trial
- Oropharyngeal cancer mortality in the United States, 1999-2023: a surveillance analysis using CDC WONDER.Frontiers in oncology · 2026Article
- Risk factors associated with oral Human Papillomavirus (HPV) prevalence within a young adult population.BMC public health · 2024Observational
- Prevalence and determinants of cervicovaginal, oral, and anal HPV infection in a population of transgender and gender diverse people assigned female at birth.medRxiv : the preprint server for health sciences · 2023Article
- Transmission and clearance of human papillomavirus infection in the oral cavity and its role in oropharyngeal carcinoma - A review.Reviews in medical virology · 2023Review
- Prevalence of HPV-DNA and E6 mRNA in lung cancer of HIV-infected patients.Scientific reports · 2022Article
- Incidence and clearance of oral and cervicogenital HPV infection: longitudinal analysis of the MHOC cohort study.BMJ open · 2022Article
- Oral and oropharyngeal high-risk HPV prevalence, HIV status, and risk behaviours in a cohort of South African men who have sex with men.AIMS public health · 2022Article
- Article
- Genotype Distribution and Prevalence of Human Papillomavirus in Head and Neck Cancer Samples from Istanbul, Turkey.Pathogens (Basel, Switzerland) · 2021Article
- No association between HPV-status in tonsillar tissue and sexual behavior of the patients in a northern German population - Critical view of the link between HPV natural history and HPV-driven carcinogenesis.Papillomavirus research (Amsterdam, Netherlands) · 2020Article
- Joint effect of tobacco, alcohol, and oral HPV infection on head and neck cancer risk in the French West Indies.Cancer medicine · 2020Article
- Quantitative Oral HPV16 and HPV18 Detection in Persons Attending Dental Clinics.Sexually transmitted diseases · 2020Article
- Low concordance of oral and genital HPV infection among male patients with sexually transmitted infections in Vietnam.BMC infectious diseases · 2019Article
- Human Papillomavirus Detection in Head and Neck Squamous Cell Carcinomas at a Tertiary Hospital in Sub-Saharan Africa.TheScientificWorldJournal · 2019Article
- Awareness of head and neck cancer - a multicentre survey among young respondents in Poland.International dental journal · 2018Article
- Risk Factors for Oral Human Papillomavirus Infection Among Young Men Who Have Sex With Men-2 Cities, United States, 2012-2014.Sexually transmitted diseases · 2018Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundLittle is known about the rates and determinants of oral human papillomavirus (HPV) infection, an infection that is etiologically linked with oropharyngeal cancers.
methodsA cohort of male university students (18-24 years) was examined every 4 months (212 men, 704 visits). Oral specimens were collected via gargle/rinse and swabbing of the oropharynx. Genotyping for HPV-16 and 36 other α-genus types was performed by polymerase chain reaction-based assay. Data on potential determinants were gathered via clinical examination, in-person questionnaire, and biweekly online diary. Hazards ratios (HR) were used to measure associations with incident infection.
resultsPrevalence of oral HPV infection at enrollment was 7.5%, and 12-month cumulative incidence was 12.3% (95% confidence interval [CI], 7.0, 21.3). Prevalence of oral HPV-16 was 2.8% and 12-month cumulative incidence was 0.8% (95% CI, 0.1%-5.7%). None of the incident oral HPV infections and 28.6% of the prevalent oral HPV infections were detected more than once. In a multivariate model, incident oral HPV infection was associated with recent frequency of performing oral sex (≥1 per week: HR, 3.7; 95% CI, 1.4-9.8), recent anal sex with men (HR, 42.9; 95% CI, 8.8-205.5), current infection with the same HPV type in the genitals (HR, 6.2; 95% CI, 2.4-16.4), and hyponychium (HR, 11.8, 95% CI, 4.1-34.2).
conclusionsAlthough nearly 20% of sexually active male university students had evidence of oral HPV infection within 12 months, most infections were transient. Human papillomavirus type 16 was not common. Sexual contact and autoinoculation appeared to play independent roles in the transmission of α-genus HPV to the oral cavity of young men.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.