ArticleJournal of endodontics2012
Large-scale clinical endodontic research in the National Dental Practice-Based Research Network: study overview and methods.
Article in Journal of endodontics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- Collaboration between The National Dental Practice-Based Research Network and the American Association of Endodontists: Impact on the endodontic literature.Journal of the American Dental Association (1939) · 2026Article
- Root-Filled Teeth With and Without Pain in a Cohort of Individuals Scheduled for Regular Dental Check-Ups. A Matched Case-Control Study.Journal of oral rehabilitation · 2026Article
- Occurrence and predictors of severe pain one week after root canal treatment: the national dental PBRN PREDICT endodontic study.Journal of dentistry · 2026Article
- Prevalence and factors associated with severe pre-operative pain among patients presenting for non-surgical root canal treatment in the national dental PBRN PREDICT endodontic study.Journal of dentistry · 2025Article
- Danish endodontic practice-based research network: follow-up data.Acta odontologica Scandinavica · 2025Article
- Characteristics and impact of pain from root-filled teeth. A practice-based cross-sectional study comparing painful teeth with and without signs of inflammatory dental disease.Journal of oral & facial pain and headache · 2024Article
- Fast self-curing α-tricalcium phosphate/β-dicalcium silicate composites beneficial for root canal sealing treatment.Heliyon · 2022Article
- Present status and future directions of intracanal medicaments.International endodontic journal · 2022Review
- Health and science: evidence, policy and advocacy.British dental journal · 2022Article
- Preoperative Factors Associated with Anesthesia Failure for Patients Undergoing Nonsurgical Root Canal Therapy: A National Dental Practice-Based Research Network Study.Journal of endodontics · 2021Article
- 3-year Outcome of Patients with Persistent Pain after Root Canal Treatment: The National Dental Practice-Based Research Network.Journal of endodontics · 2020Article
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- Validity of Preoperative Clinical Findings to Identify Dental Pulp Status: A National Dental Practice-Based Research Network Study.Journal of endodontics · 2016Article
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- Article
- Differential diagnoses for persistent pain after root canal treatment: a study in the National Dental Practice-based Research Network.Journal of endodontics · 2015Article
- Predicting severe pain after root canal therapy in the National Dental PBRN.Journal of dental research · 2015Observational
- Root canal therapy reduces multiple dimensions of pain: a national dental practice-based research network study.Journal of endodontics · 2014Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 1 country.
Funding
Abstract
introductionThis article reports on the feasibility of conducting a large-scale endodontic prospective cohort study in The National Dental Practice-Based Research Network. This study was designed to measure pain and burden associated with initial orthograde root canal therapy (RCT) and to explore potential prognostic factors for pain outcomes. The main objectives of this first report in a series are to describe the project's feasibility and methods and the demographics of the sample obtained.
methodsSixty-two dentist practitioner-investigators (ie, 46 generalists and 16 endodontists) in 5 geographic areas were certified within the network and trained regarding the standardized study protocol. Enrollment and baseline data collection occurred over 6 months with postobturation follow-up for another 6 months. Patients and dentists completed questionnaires before and immediately after treatment visits. Patients also completed questionnaires at 1 week, 3 months, and 6 months after obturation.
resultsEnrollment exceeded target expectations, with 708 eligible patient-participants. Questionnaire return rates were good, ranging between 90% and 100%. Patient demographics were typical of persons who receive RCT in the United States (ie, mean age = 48 years [standard deviation = 13 years], with most being female [59%], college educated [81%], white non-Hispanic [86%], and having dental insurance [81%]). The tooth types being treated were also typical (ie, 61% molars, 28% premolars, and 11% anteriors, with maxillary teeth being predominant [59%]).
conclusionsThis study shows the feasibility of conducting large-scale endodontic prospective cohort studies in the network. Patients were rapidly recruited with high levels of compliance in data collection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.