Evidence map›Paper›PMID 23062626›Full record

ReviewCurrent opinion in genetics & development2012

Reprogramming and development in nuclear transfer embryos and in interspecific systems.

Patrick Narbonne, Kei Miyamoto, J B Gurdon

Abstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Various nuclear reprogramming systems using egg and oocyte materials.The Journal of reproduction and development · 2019
    Review
  6. Article
  7. Article
  8. Healthy ageing of cloned sheep.Nature communications · 2016
    Article
  9. Article
  10. Epigenetics in kidney development and renal disease.Translational research : the journal of laboratory and clinical medicine · 2015
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Epigenetics of cellular reprogramming.Current opinion in genetics & development · 2013
    Review
  17. The ups and downs of somatic cell nucleus transfer (SCNT) in humans.Journal of assisted reproduction and genetics · 2013
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patrick NarbonneThe Wellcome Trust/Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Cambridge, United Kingdom.
Kei Miyamoto
J B Gurdon

Funding

Medical Research Council G1001690Wellcome Trust 079948Wellcome Trust 092096
6 · The paper itself

Abstract

Nuclear transfer (NT) remains the most effective method to reprogram somatic cells to totipotency. Somatic cell nuclear transfer (SCNT) efficiency however remains low, but recurrent problems occurring in partially reprogrammed cloned embryos have recently been identified and some remedied. In particular, the trophectoderm has been identified as a lineage whose reprogramming success has a large influence on SCNT embryo development. Several interspecific hybrid and cybrid reprogramming systems have been developed as they offer various technical advantages and potential applications, and together with SCNT, they have led to the identification of a series of reprogramming events and responsible reprogramming factors. Interspecific incompatibilities hinder full exploitation of cross-species reprogramming systems, yet recent findings suggest that these may not constitute insurmountable obstacles.

Indexed as

Cellular ReprogrammingGene Expression Regulation, DevelopmentalNuclear Transfer TechniquesAnimalsCell NucleusCloning, MolecularEmbryo, MammalianEmbryonic DevelopmentHumans

Identifiers

PMID23062626
PMCPMC3654497

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.