ArticleQuantitative imaging in medicine and surgery2012
Ultrasound for molecular imaging and therapy in cancer.
Article in Quantitative imaging in medicine and surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 61 citations in OpenAlex.
- Focused ultrasound in modern medicine: bioengineering interfaces, molecular effects, and clinical breakthroughs.Frontiers in bioengineering and biotechnology · 2025Review
- Mechanistic Insights and Therapeutic Delivery through Micro/Nanobubble-Assisted Ultrasound.Pharmaceutics · 2022Review
- Experimental acoustic characterization of an endoskeletal antibubble contrast agent: First results.Medical physics · 2021Article
- Design and Challenges of Sonodynamic Therapy System for Cancer Theranostics: From Equipment to Sensitizers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Accurately Controlled Delivery of Temozolomide by Biocompatible UiO-66-NHInternational journal of nanomedicine · 2021Article
- Red blood cell membrane-enveloped OTheranostics · 2020Article
- Real-time intraoperative ultrasound in brain surgery: neuronavigation and use of contrast-enhanced image fusion.Quantitative imaging in medicine and surgery · 2019Article
- Drug-Loaded Microbubbles Combined with Ultrasound for Thrombolysis and Malignant Tumor Therapy.BioMed research international · 2019Review
- Nanoparticle-assisted ultrasound: A special focus on sonodynamic therapy against cancer.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2018Article
- Intraoperative ultrasound in spine surgery: history, current applications, future developments.Quantitative imaging in medicine and surgery · 2018Article
- Targeted delivery of reduced graphene oxide nanosheets using multifunctional ultrasound nanobubbles for visualization and enhanced photothermal therapy.International journal of nanomedicine · 2018Article
- Ultrasound Molecular Imaging With BR55 in Patients With Breast and Ovarian Lesions: First-in-Human Results.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017Article
- Structure-Inherent Targeting of Near-Infrared Fluorophores for Image-Guided Surgery.Chonnam medical journal · 2017Review
- Article
- Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa.Cancer cell international · 2017Review
- Theragnostic ultrasound using microbubbles in the treatment of prostate cancer.Ultrasonography (Seoul, Korea) · 2016Review
- Imaging-guided delivery of RNAi for anticancer treatment.Advanced drug delivery reviews · 2016Review
- High Resolution Ultrasound and Photoacoustic Imaging of Orthotopic Lung Cancer in Mice: New Perspectives for Onco-Pharmacology.PloS one · 2016Article
- Intraoperative Contrast Enhanced Ultrasound Evaluates the Grade of Glioma.BioMed research international · 2016Article
- Combining in Vitro Diagnostics with in Vivo Imaging for Earlier Detection of Pancreatic Ductal Adenocarcinoma: Challenges and Solutions.Radiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Over the past decade, molecularly-targeted contrast enhanced ultrasound (ultrasound molecular imaging) has attracted significant attention in preclinical research of cancer diagnostic and therapy. Potential applications for ultrasound molecular imaging run the gamut from early detection and characterization of malignancies to monitoring treatment responses and guiding therapies. There may also be a role for ultrasound contrast agents for improved delivery of chemotherapeutic drugs and gene therapies across biological barriers. Currently, a first Phase 0 clinical trial in patients with prostate cancer assesses toxicity and feasibility of ultrasound molecular imaging using contrast agents targeted at the angiogenic marker vascular endothelial growth factor receptor type 2 (VEGFR2). This mini-review highlights recent advances and potential applications of ultrasound molecular imaging and ultrasound-guided therapy in cancer.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.