ArticleMobile genetic elements2012
Large-scale dynamics of horizontal transfers.
Article in Mobile genetic elements, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed.
- Metacommunity structure preserves genome diversity in the presence of gene-specific selective sweeps under moderate rates of horizontal gene transfer.PLoS computational biology · 2023Article
- Review
- Family-specific scaling laws in bacterial genomes.Nucleic acids research · 2017Article
- Cross-species gene-family fluctuations reveal the dynamics of horizontal transfers.Nucleic acids research · 2014Article
- Physiology of the read-write genome.The Journal of physiology · 2014Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The widespread exchange of genes between bacteria must have consequences on the global architecture of their genomes, which are being found in the abundant genomic data available today. Most of the expansion of bacterial protein families can be attributed to transfer events, which are positively biased for smaller evolutionary distances between genomes, and more frequent for classes that are larger, when summed over all known bacteria. Moreover, "innovation" events where horizontal transfers carry exogenous evolutionary families appear to be less frequent for larger genomes. This dynamic expansion of evolutionary families is interconnected with the acquisition of new biological functions and thus with the size and distribution of the genes' functional categories found on a genome. This commentary presents our recent contributions to this line of work and possible future directions.
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Registered trials
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