Evidence map›Paper›PMID 23060780›Full record

ArticleFrontiers in computational neuroscience2012

Computational models of neuron-astrocyte interaction in epilepsy.

Vladislav Volman, Maxim Bazhenov, Terrence J Sejnowski

Abstract read
In one paragraph

Article in Frontiers in computational neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Neuron-astrocyte associative memory.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Building transformers from neurons and astrocytes.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Seizure prediction - ready for a new era.Nature reviews. Neurology · 2018
    Review
  15. Computational Models for Calcium-Mediated Astrocyte Functions.Frontiers in computational neuroscience · 2018
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vladislav VolmanComputational Neurobiology Laboratory, Howard Hughes Medical Institute, The Salk Institute for Biological Studies La Jolla, CA, USA ; Center for Theoretical Biological Physics, University of California at San Diego La Jolla, CA, USA ; L-3 Applied Technologies/Simulation, Engineering, and Testing San Diego, CA, USA.
Maxim Bazhenov
Terrence J Sejnowski

Funding

Intrinsic and synaptic mechanisms of epileptogenesis triggered by cortical traumaR01NS059740 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI SEJNOWSKI, TERRENCE J · 2009 to 2012
$1.6M
Cortical mechanisms and functional role of slow sleep oscillationsR01NS060870 · NINDS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI BAZHENOV, MAKSIM V · 2008 to 2011
$1.3M
NINDS NIH HHS R01 NS059740NINDS NIH HHS R01 NS060870
6 · The paper itself

Abstract

Astrocytes actively shape the dynamics of neurons and neuronal ensembles by affecting several aspects critical to neuronal function, such as regulating synaptic plasticity, modulating neuronal excitability, and maintaining extracellular ion balance. These pathways for astrocyte-neuron interaction can also enhance the information-processing capabilities of brains, but in other circumstances may lead the brain on the road to pathological ruin. In this article, we review the existing computational models of astrocytic involvement in epileptogenesis, focusing on their relevance to existing physiological data.

Indexed as

astrocytesepileptogenesisinflammationregulatory signalingtrauma

Identifiers

PMID23060780
PMCPMC3459315

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.