Evidence map›Paper›PMID 23060684›Full record

ArticleAphasiology2012

Can tDCS enhance treatment of aphasia after stroke?

Rachel Holland, Jenny Crinion

3 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Aphasiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02249819 phase1 / phase2terminatednot on this mapstarted 2014, after this paper: background citation

Evaluating Anodal tDCS Preceding Aphasia Therapy

TypeinterventionalSponsorNorthwell HealthRan2014 to 2017Enrolled15ConditionsStroke, AphasiaArmstranscranial direct current stimulation
NCT04166513 nacompletednot on this mapstarted 2019, after this paper: background citation

Effects of tDCS in Language Recovery and Reorganization in Chronic Aphasia

TypeinterventionalSponsorMedical College of WisconsinRan2019 to 2024Enrolled25ConditionsStroke, AphasiaArmsTargeted Transcranial Direct Current Stimulation, Active Control Transcranial Direct Current Stimulation, Phonologic-Focused Speech Therapy, Semantic-Focused Speech Therapy
NCT06010030 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

A Randomized Clinical Trial of tDCS to Remediate Phonological Impairment in Aphasia

TypeinterventionalSponsorMedical College of WisconsinRan2023 to 2033Enrolled200ConditionsAphasia, StrokeArmsTargeted Transcranial Direct Current Stimulation, Speech Therapy
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 136 citations in OpenAlex.

  1. Pooled it
  2. Diagnosing and managing post-stroke aphasia.Expert review of neurotherapeutics · 2021
    Trial
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  4. Using tDCS to facilitate motor learning in speech production: The role of timing.Cortex; a journal devoted to the study of the nervous system and behavior · 2019
    Trial
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  11. The mental cost of cognitive enhancement.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Trial
  12. Article
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  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rachel HollandInstitute of Cognitive Neuroscience, University College London, London, UK.
Jenny Crinion
University College London · GB

Funding

Medical Research Council G0701888
6 · The paper itself

Abstract

backgroundRecent advances in the application of transcranial direct current stimulation (tDCS) in healthy populations have led to the exploration of the technique as an adjuvant method to traditional speech therapies in patients with post-stroke aphasia.

aimsTHE PURPOSE OF THE REVIEW IS: (i) to review the features of tDCS that make it an attractive tool for research and potential future use in clinical contexts; (ii) to describe recent studies exploring the facilitation of language performance using tDCS in post-stroke aphasia; (iii) to explore methodological considerations of tDCS that may be key to understanding tDCS in treatment of aphasia post stroke; and (iv) to highlight several caveats and outstanding questions that need to be addressed in future work. MAIN CONTRIBUTION: This review aims to highlight our current understanding of the methodological and theoretical issues surrounding the use of tDCS as an adjuvant tool in the treatment of language difficulties after stroke.

conclusionsPreliminary evidence shows that tDCS may be a useful tool to complement treatment of aphasia, particularly for speech production in chronic stroke patients. To build on this exciting work, further systematic research is needed to understand the mechanisms of tDCS-induced effects, its application to current models of aphasia recovery, and the complex interactions between different stimulation parameters and language rehabilitation techniques. The potential of tDCS is to optimise language rehabilitation techniques and promote long-term recovery of language. A stimulating future for aphasia rehabilitation!

Identifiers

PMID23060684
PMCPMC3464450
OpenAlexW2092692413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.