Evidence map›Paper›PMID 23059871›Full record

ReviewCancer gene therapy2012

Will T-cell therapy for cancer ever be a standard of care?

M K Brenner

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Cancer gene therapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02667093 (Bone Marrow and Peripheral Blood), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02667093 unknown statusnot on this mapstarted 2013, after this paper: background citation

Bone Marrow and Peripheral Blood (PB) Samples From Patients With Leukemia and PB From Their BM Donors (BMD) to Identify Leukemia-Specific Antigens (LSA) and Graft Versus Host Disease Antigens (GVHDA) for Use in Cellular Immunotherapy

TypeobservationalSponsorPersImmune, IncRan2013 to 2020Enrolled50ConditionsAcute Myeloid Leukemia
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. CD4Journal of cancer research and clinical oncology · 2023
    Article
  4. Review
  5. Review
  6. Review
  7. Gene therapy on the move.EMBO molecular medicine · 2013
    Review
  8. Collapse of the tumor stroma is triggered by IL-12 induction of Fas.Molecular therapy : the journal of the American Society of Gene Therapy · 2013
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

M K BrennerCenter for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, The Methodist Hospital, Houston, TX 77030, USA. mbrenner@bcm.edu

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI PAVAN REDDY · 2007 to 2026
$73.9M
Tissue ResourceP50CA126752 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Andrea Nicole Marcogliese · 2007 to 2026
$51.4M
VECTOR PRODUCTIONP01CA094237 · NCI · BAYLOR COLLEGE OF MEDICINE · PI HESLOP, HELEN E, ROONEY, CLIONA M. · 2002 to 2017
$27.8M
NCI NIH HHS P30 CA125123
6 · The paper itself

Abstract

Cellular therapies for cancer are showing increasing efficacy but their introduction as a 'standard of care' for these disorders is hampered by technical, regulatory and financial concerns. This review identifies some of the major problems and suggests potential solutions.

Indexed as

HumansImmunotherapy, AdoptiveNeoplasmsStandard of CareT-Lymphocytes

Identifiers

PMID23059871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.