Evidence map›Paper›PMID 23059701›Full record

Trial reportClinical rehabilitation2013

Communication and Low Mood (CALM): a randomized controlled trial of behavioural therapy for stroke patients with aphasia.

Shirley A Thomas, Marion F Walker, Jamie A Macniven, Helen Haworth, Nadina B Lincoln

Open access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Clinical rehabilitation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 6 pooled it
4.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 6 syntheses or guidelines pooled it, 152 citations in OpenAlex.

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  9. Preventing depression in aphasia: A cluster randomized control trial of the Aphasia Action Success Knowledge (ASK) program.International journal of stroke : official journal of the International Stroke Society · 2023
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  20. Improving How Healthcare Staff Support the Psychological Well-Being of People Living With Post-Stroke Aphasia: A Co-Created Study.Health expectations : an international journal of public participation in health care and health policy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Shirley A ThomasUniversity of Nottingham, Nottingham NG8 1BB, UK. Shirley.thomas@nottingham.ac.uk
Marion F Walker
Jamie A Macniven
Helen Haworth
Nadina B Lincoln
University of Nottingham · GBNottinghamshire Healthcare NHS Foundation Trust · GBNottingham University Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim was to evaluate behavioural therapy as a treatment for low mood in people with aphasia.

designA randomized controlled trial comparing behavioural therapy plus usual care with a usual care control. Potential participants with aphasia after stroke were screened for the presence of low mood. Those who met the criteria and gave consent were randomly allocated.

settingParticipants were recruited from hospital wards, community rehabilitation, speech and language therapy services and stroke groups. SUBJECTS: Of 511 people with aphasia identified, 105 had low mood and were recruited.

interventionsBehavioural therapy was offered for up to three months. Outcomes were assessed three and six months after random allocation. MAIN MEASURES: Stroke Aphasic Depression Questionnaire, Visual Analog Mood Scales 'sad' item, and Visual Analogue Self-Esteem Scale.

resultsParticipants were aged 29 to 94 years (mean 67.0, SD 13.5) and 66 (63%) were men. Regression analysis showed that at three months, when baseline values and communication impairment were controlled for, group allocation was a significant predictor of the Stroke Aphasic Depression Questionnaire (P < 0.05), visual analogue 'sad' (P = 0.03), and Visual Analogue Self-Esteem Scale (P < 0.01). At six months, group alone was a significant predictor of the Stroke Aphasic Depression Questionnaire (P < 0.05), and remained significant when baseline values were controlled for (P = 0.02). Mean Stroke Aphasic Depression Questionnaire 10-item hospital version scores decreased from baseline to six months by six points in the intervention group as compared with an increase of 1.9 points in the control group.

conclusionsBehavioural therapy seemed to improve the mood of people with aphasia.

Indexed as

Stroke RehabilitationAdultAgedAged, 80 and overAphasiaCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedMood DisordersRegression AnalysisROC CurveSelf ConceptStatistics, NonparametricStroke

Identifiers

PMID23059701
PMCPMC3652643
OpenAlexW2095758871

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.