Evidence map›Paper›PMID 23059001›Full record

ReviewTrends in cell biology2012

Engineered, harnessed, and hijacked: synthetic uses for cytoskeletal systems.

Brian S Goodman, Nathan D Derr, Samara L Reck-Peterson

Abstract readReview
In one paragraph

Review in Trends in cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Molecular Encapsulation Inside Microtubules Based on Tau-Derived Peptides.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brian S GoodmanDepartment of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
Nathan D Derr
Samara L Reck-Peterson
Harvard University · US

Funding

Cellular Control of Microtubule-Based Transport: Unraveling its Molecular MechanDP2OD004268 · OD · HARVARD MEDICAL SCHOOL · PI RECK-PETERSON, SAMARA L · 2008 to 2008
$2.5M
NIH HHS DP2 OD004268
6 · The paper itself

Abstract

Synthetic biology re-imagines existing biological systems by designing and constructing new biological parts, devices, and systems. In the arena of cytoskeleton-based transport, synthetic approaches are currently used in two broad ways. First, molecular motors are harnessed for non-physiological functions in cells. Second, transport systems are engineered in vitro to determine the biophysical rules that govern motility. These rules are then applied to synthetic nanotechnological systems. We review recent advances in both of these areas and conclude by discussing future directions in engineering the cytoskeleton and its motors for transport.

Indexed as

AnimalsBiological TransportCell MembraneCell MovementCytoskeletonDyneinsGenetic EngineeringKinesinsMolecular Motor ProteinsPolymerizationProtein Structure, TertiarySynthetic BiologyVirus DiseasesVirusesDyneinsKinesinsMolecular Motor Proteins

Identifiers

PMID23059001
PMCPMC3505249
OpenAlexW2090393740

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.