ArticleThe American journal of pathology1990
Chromogranin A and B gene expression in carcinomas of the breast. Correlation of immunocytochemical, immunoblot, and hybridization analyses.
Article in The American journal of pathology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 32 citations in OpenAlex.
- Breast cancer with neuroendocrine differentiation: an update based on the latest WHO classification.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021Review
- Locally-advanced primary neuroendocrine carcinoma of the breast: case report and review of the literature.World journal of surgical oncology · 2013Article
- Functional nsSNPs from carcinogenesis-related genes expressed in breast tissue: potential breast cancer risk alleles and their distribution across human populations.Human genomics · 2006Article
- Chromogranin A and chromogranin B in noninvasive and invasive breast carcinoma.Endocrine pathology · 2002Article
- Classic and recent special stains used in differential diagnosis of endocrine tumors.Endocrine pathology · 2001Review
- Prevalence and Prognostic Significance of Neuroendocrine Differentiation in Colorectal Carcinomas.Endocrine pathology · 1998Article
- The Pathology of Medullary Carcinoma of the Thyroid: Review of the Literature and Personal Experience on 62 Cases.Endocrine pathology · 1996Article
- The granin protein family: markers for neuroendocrine cells and tools for the diagnosis of neuroendocrine tumors.Journal of endocrinological investigation · 1994Review
- PIP/GCDFP-15 gene expression and apocrine differentiation in carcinomas of the breast.Virchows Archiv : an international journal of pathology · 1994Article
- Primary oat cell (neuroendocrine) carcinoma of the breast. Report of four cases.Virchows Archiv. A, Pathological anatomy and histopathology · 1992Article
- Immunoreactivities for chromogranin A and B, and secretogranin II in the guinea pig entero-endocrine system: cellular distributions and intercellular heterogeneities.Cell and tissue research · 1991Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chromogranins (Cg) are regarded as specific neuroendocrine (NE) markers in cells and tumors. Expression of CgA and CgB genes has been demonstrated by correlative immunocytochemical, immunoblotting, in situ hybridization, and Northern blot procedures in seven argyrophilic breast carcinomas, while eight control cases of ductal carcinomas, not otherwise specified, were negative. A high degree of correlation was observed between the various techniques revealing CgA and/or CgB gene expression at different levels; minor discrepancies might be related to tumor heterogeneity or to technical factors. The present study, confirming previous investigations, establishes NE differentiation in a group of human breast cancers. The identification of this type of tumors, especially by testing chromogranin(s) production, appears to be of both biologic and clinical interest.
Indexed as
Identifiers
2305832PMC1877399W126492077What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.