Evidence map›Paper›PMID 23058040›Full record

ReviewTrends in biochemical sciences2012

Membrane curvature and its generation by BAR proteins.

Carsten Mim, Vinzenz M Unger

Abstract readReview
In one paragraph

Review in Trends in biochemical sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 160 papers.

0numbers the graph read from it
0cells of the map it votes in
160citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

160 citing papers in PubMed.

  1. Review
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  7. Sorting nexin 5 mediates antigen presentation and immunity againstbioRxiv : the preprint server for biology · 2026
    Article
  8. Review
  9. Article
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  12. Review
  13. From Cap to Collar: Ontogeny of the Endocytic Collar inJournal of fungi (Basel, Switzerland) · 2025
    Article
  14. Review
  15. Bend it like BIN1: how a membrane-curving adaptor protein shapes cardiac physiology.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

100 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carsten MimDepartment of Molecular Biosciences, Northwestern University, 2205 Campus Drive, Evanston, IL 60208, USA.
Vinzenz M Unger

Funding

Structural Biology of Membrane ScaffoldsR01GM094479 · NIGMS · NORTHWESTERN UNIVERSITY · PI UNGER, VINZENZ · 2010 to 2013
$1.6M
NIGMS NIH HHS R01 GM094479
6 · The paper itself

Abstract

Membranes are flexible barriers that surround the cell and its compartments. To execute vital functions such as locomotion or receptor turnover, cells need to control the shapes of their membranes. In part, this control is achieved through membrane-bending proteins, such as the Bin/amphiphysin/Rvs (BAR) domain proteins. Many open questions remain about the mechanisms by which membrane-bending proteins function. Addressing this shortfall, recent structures of BAR protein:membrane complexes support existing mechanistic models, but also produced novel insights into how BAR domain proteins sense, stabilize, and generate curvature. Here we review these recent findings, focusing on how BAR proteins interact with the membrane, and how the resulting scaffold structures might aid the recruitment of other proteins to the sites where membranes are bent.

Indexed as

Adaptor Proteins, Signal TransducingAnimalsCell MembraneDrosophila ProteinsEndocytosisForkhead Transcription FactorsHumansMembrane ProteinsNerve Tissue ProteinsProtein Structure, TertiaryAdaptor Proteins, Signal Transducingamphiphysinbin protein, DrosophilaDrosophila ProteinsForkhead Transcription FactorsMembrane ProteinsNerve Tissue Proteins

Identifiers

PMID23058040
PMCPMC3508348

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.