Evidence map›Paper›PMID 23057654›Full record

Trial reportCongestive heart failure (Greenwich, Conn.)

Tai chi in patients with heart failure with preserved ejection fraction.

Gloria Y Yeh, Malissa J Wood, Peter M Wayne, Mary T Quilty, Lynne W Stevenson, Roger B Davis, Russell S Phillips, Daniel E Forman

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Congestive heart failure (Greenwich, Conn.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04019301 (Caring for Caregivers With Mind-body Exercise), which is not on this map. Cited by 42 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 14 pooled it
14.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04019301 naunknown statusnot on this map

Caring for Caregivers With Mind-body Exercise

TypeinterventionalSponsorUniversity of HoustonRan2019 to 2022Enrolled47ConditionsCaregiver Distress, Physical Function, Quality of LifeArmsBaduanjin Qigong, Community-based, Baduanjin Qigong, Internet-based
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 14 syntheses or guidelines pooled it, 84 citations in OpenAlex.

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  18. Functional benefits of tai chi training in senior housing facilities.Journal of the American Geriatrics Society · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Gloria Y YehOsher Center for Integrative Medicine, Harvard Medical School, Boston, MA, USA.
Malissa J Wood
Peter M Wayne
Mary T Quilty
Lynne W Stevenson
Roger B Davis
Russell S Phillips
Daniel E Forman
Brigham and Women's Hospital · USBeth Israel Deaconess Medical Center · USMassachusetts General Hospital · US

Funding

ZINC STATUS AND T CELL DISORDER IN MILD HUMAN ZINC DEFICIENCYM01RR001032 · NCRR · BETH ISRAEL DEACONESS MEDICAL CENTER · PI JEZEWSKI, PETER ALAN · 1985 to 2008
$32.3M
Mind-Body Exercise in the Management of Cardiac DiseaseK23AT002624 · NCCIH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI YEH, GLORIA Y · 2005 to 2009
$650k
NCCIH NIH HHS K23 AT00002624NCCIH NIH HHS K23 AT002624NCRR NIH HHS M01 RR001032NCRR NIH HHS RR 01032
6 · The paper itself

Abstract

Although exercise is an important component of heart failure management, optimal regimens, particularly in heart failure with preserved ejection fraction (HFPEF), are uncertain. Tai chi (TC) is a mind-body exercise that may have potential benefits but has not been studied in this population. The authors randomized 16 patients with HFPEF to either 12 weeks TC or aerobic exercise. Assessments included peak oxygen uptake, 6-minute walk, quality of life, echocardiography, mood, and self-efficacy at baseline and at 12 weeks. Cardiorespiratory measures during exercise were obtained to characterize training intensities. Baseline characteristics were as follows: age 66±12 years, E/A ratio 1.3±0.7, and E/e' ratio 15.9±4.8. Overall, adherence was excellent (89% attendance). Change in peak oxygen uptake was similar between groups after 12 weeks, but 6-minute walk distance increased more after TC (69±46 m vs 10±31 m, P=.02). While both groups had improved Minnesota Living With Heart Failure scores and self-efficacy, Profile of Mood States (POMS)-Depression scores improved more with TC (-1.7±2.8 vs 1.6±3, P=.05). Cardiorespiratory assessment during TC showed lower oxygen uptake (4.3 mL/kg/min vs 9.4 mL/kg/min, P<.01), respiratory rate, and heart rate. TC is feasible and safe in HFPEF. Therepeutic endpoints appear similar with TC relative to aerobic exercise despite a lower aerobic training workload.

Indexed as

ExerciseHeart FailureAffectAgedEchocardiographyExercise ToleranceFemaleHumansMaleMiddle AgedMonitoring, PhysiologicOxygen ConsumptionQuality of LifeSelf EfficacyTai JiTreatment Outcome

Identifiers

PMID23057654
PMCPMC3546234
OpenAlexW1884805488

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.