ArticleIranian journal of pediatrics2012
Early versus Late Trophic Feeding in Very Low Birth Weight Preterm Infants.
Article in Iranian journal of pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06883903 (The Effect of Day-Night Cycle on the Transition Time to Full Enteral Feeding in Preterm Newborns Receiving Oropharyngeal Colostrum), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Day-Night Cycle on the Transition Time to Full Enteral Feeding in Preterm Newborns Receiving Oropharyngeal Colostrum
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Nutritional management of neonates who undergo major surgery for gastrointestinal disorders: a joint position paper of the Italian Society of Neonatology (SIN), the Italian Society of Pediatric Surgery (SICP), and the Italian Society of Pediatric Nutrition (SINUPE).Italian journal of pediatrics · 2026Guideline
- Pooled it
- Analysis of factors affecting postoperative feeding intolerance in neonates following intestinal surgery.BMC pediatrics · 2026Article
- How long does it take to start minimal enteral feeding in preterm Neonates admitted to NICUs in Southern Oromia, Ethiopia?Italian journal of pediatrics · 2025Observational
- Trophic feeding initiation and its predictors in preterm neonates admitted to Neonatal Intensive Care Units: Multicenter study, Addis Ababa.SAGE open medicine · 2025Article
- Article
- Predictors of time to full enteral feeding in low birth weight neonates admitted to neonatal intensive care unit: a prospective follow up study.BMC pediatrics · 2024Article
- Risk factors of necrotizing enterocolitis among neonates admitted to the neonatal intensive care unit at the selected public hospitals in southern Ethiopia, 2023.Frontiers in pediatrics · 2024Article
- Early Enteral Feeding of the Preterm Infant-Delay until Own Mother's Breastmilk Becomes Available? (Israel, 2012-2017).Nutrients · 2022Article
- Article
- Necrotizing Enterocolitis and Its Predictors Among Preterm Neonates Admitted in Neonatal Intensive Care Units of Gurage Zone Public Hospitals, Southwest Ethiopia, 2021.Pediatric health, medicine and therapeutics · 2022Article
- Initiation of Breast Milk Expression and Associated Factors Among Mothers of Preterm and Low Birth Weight Neonates Admitted to Neonatal Intensive Care Units of Government Hospitals in Addis Ababa, Ethiopia,2020.Pediatric health, medicine and therapeutics · 2021Article
- Cost-effectiveness of probiotics for necrotizing enterocolitis prevention in very low birth weight infants.Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- Optimizing Nutrition in Preterm Low Birth Weight Infants-Consensus Summary.Frontiers in nutrition · 2017Review
- Evidence-based feeding strategies before and after the development of necrotizing enterocolitis.Expert review of clinical immunology · 2014Review
- Time to Initiate Trophic Feeding and Its Predictors Among Preterm Infants at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.Sage open pediatricsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveImproved survival of preterm infants, beneficial effects of trophic feeding and limited data on timing management of enteral feeding for very low birth weight preterm infants requires more researches to determine the exact starting time and increased volumes. This study aims to compare early (<48 h) versus late (>72h) trophic feeding with respect to important neonatal outcomes.
methodsIn a cohort study from September 2007 to October 2008, a total of 170 preterm infants (1000-1500 gram, 26-31 weeks) consisting of 125 who received trophic feeding enterally within the first 48 hours of birth (early group) and 45 fed enterally after 72 h0urs (late group), without major congenital birth defects and severe asphyxia entered the study. Bolus feeding was started in both groups at 1-2 cc/kg every 4-6 hours of human milk or preterm infant formula and was advanced 1-2 cc/kg/day if tolerated along with parenteral nutrition. Feeding intolerance, possibility of necrotizing entrocolitis (NEC), episodes of sepsis, body weight, length of NICU stay, and duration of parenteral nutrition were assessed serially.
findingsThere were no statistically significant differences in the clinical and maternal characteristics of infants in the two groups. The time to gain birth weight (13.75±5.21 vs 20.53±6.31 (P < 0.001)), duration of parenteral nutrition (9.26±4.572 days vs 14.11±6.415 days (P < 0.001)), hospital stay (12.14±8.612 vs 21.11±1.156 (P < 0.001)) were significantly shorter in early compared to late feeding group; none of the two groups experienced a high incidence of late onset sepsis (P = 0.73). There was 1 case of confirmed NEC in every group.
conclusionThe benefits of early trophic feeding shown by this study strongly support its use for the preterm infants without adding to complications.
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23056882PMC3446068What OpenQuestion holds
Registered trials
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