ArticleIranian journal of pediatrics2011
Detecting Common CFTR Mutations by Reverse Dot Blot Hybridization Method in Cystic Fibrosis First Report from Northern Iran.
Article in Iranian journal of pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Evaluating sequence data quality from the Swift Accel-Amplicon CFTR Panel.Scientific data · 2020Article
- Higher sweat chloride levels in patients with asthma: a case-control study.Indian journal of pediatrics · 2015Article
- Association of TNF-α Gene Variants With Clinical Manifestation of Cystic Fibrosis Patients of Iranian Azeri Turkish Ethnicity.Iranian journal of pediatrics · 2015Article
- Analysis of CFTR Gene Mutations in Children with Cystic Fibrosis, First Report from North-East of Iran.Iranian journal of basic medical sciences · 2013Article
- Analysis of c.3499+200TA(7_56) and D7S523 Microsatellites Linked to Cystic Fibrosis Transmembrane Regulator.International journal of molecular and cellular medicine · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCystic fibrosis and its distribution vary widely in different countries and/or ethnic groups. Common cystic fibrosis transmembrane conductance regulator (CFTR) mutations were reported from Iran, but the northern population was not or underrepresented in those studies. The aim of this study was to determine the frequency of common CFTR mutations in children from northern Iran.
methodsThirty unrelated Iranian cystic fibrosis patients aged less than 11 years and living in Mazandaran province (in Iran) were screened for 5 common CFTR gene mutations. deltaF508, N1303K, G542X, R347H and W1282X using Reverse Dot Blot method.
findingsOnly one mutation, DeltaF508, was found in 7 patients accounting for 21.7% (13/60) of alleles.
conclusionThese findings can be used for planning future screening and appropriate genetic counseling programs in Iranian CF families.
Indexed as
Identifiers
23056764PMC3446107What OpenQuestion holds
Registered trials
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