ArticleIranian journal of pediatrics2010
Analysis of viral load in children infected with human metapneumovirus.
Article in Iranian journal of pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Human Metapneumovirus (HMPV): Advances in Diagnosis, Molecular Epidemiology, and Clinical Impact of an Underrecognized Respiratory Virus.Diagnostics (Basel, Switzerland) · 2026Review
- Human metapneumovirus (hMPV) in 2025: emerging trends and insights from community and hospital-based respiratory panel analyses-a comprehensive review.Virology journal · 2025Review
- Article
- Transient blindness due to mild reversible encephalopathy in a 7-year-old boy.Clinical case reports · 2024Article
- Epidemiology and genotypic diversity of human metapneumovirus in paediatric patients with acute respiratory infection in Beijing, China.Virology journal · 2021Article
- Association between semi-quantitative microbial load and respiratory symptoms among Thai military recruits: a prospective cohort study.BMC infectious diseases · 2018Article
- Clinical characteristics and viral load of respiratory syncytial virus and human metapneumovirus in children hospitaled for acute lower respiratory tract infection.Journal of medical virology · 2017Article
- Metapneumovirus Infections and Respiratory Complications.Seminars in respiratory and critical care medicine · 2016Review
- Albuterol Use in Children Hospitalized with Human Metapneumovirus Respiratory Infection.International journal of pediatrics · 2016Article
- Human Metapneumovirus Infection in Jordanian Children: Epidemiology and Risk Factors for Severe Disease.The Pediatric infectious disease journal · 2015Article
- Human metapneumovirus: review of an important respiratory pathogen.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2014Review
- Human metapneumovirus in patients with respiratory tract infection in Kuwait.Journal of medical virology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveHuman metapneumovirus (hMPV) is a respiratory pathogen responsible for disease and subsequent hospitalizations in young children around the world. The disease pathology, including how viral load correlates with respiratory disease severity, remains unclear. This study investigated the correlation between viral load and clinical characteristics of hMPV infections.
methodsNasopharyngeal aspirate (NPA) samples collected from 18 infants hospitalized for lower respiratory tract infections (LRTIs) in winter were tested for hMPV by reverse transcriptase polymerase chain reaction (RT-PCR) and real-time RT-PCR. Their NPA samples were collected every-other-day to monitor changes in hMPV viral load during hospitalization. Also all these 18 patients were monitored to characterize clinically their illness.
findingshMPV load was not correlated with infection severity (P=0.5, 0.9, 0.5). In contrast, the log(10) of hMPV viral load was significantly different between those lasted for 6-11 days and those for less than 5 days (P=0.01), also the significant difference was shown between those of 6-11 days duration and those of more than 11 days (P=0.006), but there was no significant difference between those lasted for less than 5 days and those for more than 11 days (P=0.4). Additionally, high hMPV viral shedding occured between 6 and 11days.
conclusionhMPV load was significantly correlated with the course of illness. The association between hMPV viral load and the course of disease suggested that hMPV is an important pathogen in lower respiratory tract infection in children. But hMPV did not always lead to more severe respiratory illness.
Indexed as
Identifiers
23056737PMC3446086W2134499501What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.