ArticlePloS one2012
Renalase's expression and distribution in renal tissue and cells.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Effect of salt intake and potassium supplementation on serum renalase levels in Chinese adults: a randomized trial.Medicine · 2014Trial
- Renalase: a novel regulator of cardiometabolic and renal diseases.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Review
- Associations of Renalase With Blood Pressure and Hypertension in Chinese Adults.Frontiers in cardiovascular medicine · 2022Article
- Cardiac-specific renalase overexpression alleviates CKD-induced pathological cardiac remodeling in mice.Frontiers in cardiovascular medicine · 2022Article
- The Effect of Renalase rs2576178 and rs10887800 Polymorphisms on Ischemic Stroke Susceptibility in Young Patients (<50 Years): A Case-Control Study and In Silico Analysis.Disease markers · 2021Article
- Serum-to-urine renalase ratio and renalase fractional excretion in healthy adults and chronic kidney disease patients.BMC nephrology · 2020Article
- The role of urinary renalase on early-stage renal damage in Chinese adults with primary hypertension.Experimental biology and medicine (Maywood, N.J.) · 2020Article
- Differences in Noradrenaline Receptor Expression Across Different Neuronal Subtypes in Macaque Frontal Eye Field.Frontiers in neuroanatomy · 2020Article
- Extracellular renalase protects cells and organs by outside-in signalling.Journal of cellular and molecular medicine · 2017Review
- Tanshinone IIA attenuates renal damage in STZ-induced diabetic rats via inhibiting oxidative stress and inflammation.Oncotarget · 2017Article
- Rs10887800 renalase gene polymorphism is associated with an increased risk of coronary artery disease in hemodialyzed patients.International urology and nephrology · 2016Article
- Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.Journal of cellular and molecular medicine · 2016Article
- Renalase contributes to the renal protection of delayed ischaemic preconditioning via the regulation of hypoxia-inducible factor-1α.Journal of cellular and molecular medicine · 2015Article
- Serum renalase is related to catecholamine levels and renal function.Clinical and experimental nephrology · 2015Article
- Article
- The association study on renalase polymorphism and hypertension: a meta-analysis.International journal of clinical and experimental medicine · 2015Article
- Normal values for urine renalase excretion in children.Pediatric nephrology (Berlin, Germany) · 2014Article
- Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.Medical science monitor : international medical journal of experimental and clinical research · 2014Review
- Magnolin protects against contrast-induced nephropathy in rats via antioxidation and antiapoptosis.Oxidative medicine and cellular longevity · 2014Article
- Construction of the coding sequence of the transcription variant 2 of the human Renalase gene and its expression in the prokaryotic system.International journal of molecular sciences · 2013Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To study renalase's expression and distribution in renal tissues and cells, renalase coded DNA vaccine was constructed, and anti-renalase monoclonal antibodies were produced using DNA immunization and hybridoma technique, followed by further investigation with immunological testing and western blotting to detect the expression and distribution of renalase among the renal tissue and cells. Anti-renalase monoclonal antibodies were successfully prepared by using DNA immunization technique. Further studies with anti-renalase monoclonal antibody showed that renalase expressed in glomeruli, tubule, mesangial cells, podocytes, renal tubule epithelial cells and its cells supernatant. Renalase is wildly expressed in kidney, including glomeruli, tubule, mesangial cells, podocytes and tubule epithelial cells, and may be secreted by tubule epithelial cells primarily.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.