Evidence map›Paper›PMID 23056227›Full record

ArticlePloS one2012

Geographic information system-based screening for TB, HIV, and syphilis (GIS-THIS): a cross-sectional study.

Neela D Goswami, Emily J Hecker, Carter Vickery, Marshall A Ahearn, Gary M Cox, David P Holland, Susanna Naggie, Carla Piedrahita, Ann Mosher, Yvonne Torres and 5 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 5 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 5 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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  16. Failure to complete treatment for latent tuberculosis infection in Portugal, 2013-2017: geographic-, sociodemographic-, and medical-associated factors.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Neela D GoswamiDepartment of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America. neela.goswami@duke.edu
Emily J Hecker
Carter Vickery
Marshall A Ahearn
Gary M Cox
David P Holland
Susanna Naggie
Carla Piedrahita
Ann Mosher
Yvonne Torres
Brianna L Norton
Sujit Suchindran
Paul H Park
Debbie Turner
Jason E Stout
Duke Medical Center · USWake County Human Services · US

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Susanna Naggie, GEORGIA Doris TOMARAS · 2005 to 2026
$50.5M
Ruth L. Kirschstein National Research Service Award (NRSA)- T32T32AI007392 · NIAID · DUKE UNIVERSITY · PI Amy Lynn Corneli, Guido Ferrari · 1990 to 2026
$9.8M
NIAID NIH HHS 5T32-AI007392-22NIAID NIH HHS P30 AI064518NIAID NIH HHS T32 AI007392PHS HHS P30A164518
6 · The paper itself

Abstract

objectiveTo determine the feasibility and case detection rate of a geographic information systems (GIS)-based integrated community screening strategy for tuberculosis, syphilis, and human immunodeficiency virus (HIV).

designProspective cross-sectional study of all participants presenting to geographic hot spot screenings in Wake County, North Carolina.

methodsThe residences of tuberculosis, HIV, and syphilis cases incident between 1/1/05-12/31/07 were mapped. Areas with high densities of all 3 diseases were designated "hot spots." Combined screening for tuberculosis, HIV, and syphilis were conducted at the hot spots; participants with positive tests were referred to the health department. RESULTS AND

conclusionsParticipants (N = 247) reported high-risk characteristics: 67% previously incarcerated, 40% had lived in a homeless shelter, and 29% had a history of crack cocaine use. However, 34% reported never having been tested for HIV, and 41% did not recall prior tuberculin skin testing. Screening identified 3% (8/240) of participants with HIV infection, 1% (3/239) with untreated syphilis, and 15% (36/234) with latent tuberculosis infection. Of the eight persons with HIV, one was newly diagnosed and co-infected with latent tuberculosis; he was treated for latent TB and linked to an HIV provider. Two other HIV-positive persons had fallen out of care, and as a result of the study were linked back into HIV clinics. Of 27 persons with latent tuberculosis offered therapy, nine initiated and three completed treatment. GIS-based screening can effectively penetrate populations with high disease burden and poor healthcare access. Linkage to care remains challenging and will require creative interventions to impact morbidity.

Indexed as

AdultCross-Sectional StudiesFeasibility StudiesFemaleFollow-Up StudiesGeographic Information SystemsGeographyHIV InfectionsHumansIncidenceMaleMass ScreeningMiddle AgedNorth CarolinaProspective StudiesSyphilis

Identifiers

PMID23056227
PMCPMC3462803
OpenAlexW2044282157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.