ArticleARYA atherosclerosis2012
Is helicobacter pylori infection a risk factor for coronary heart disease?
Article in ARYA atherosclerosis, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02317445 (Beijing Tiantan Hospital,Capital Medical University.), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Beijing Tiantan Hospital,Capital Medical University.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Beyond the gut: a comprehensive meta-analysis on Helicobacter pylori infection and cardiovascular complications.Annals of clinical microbiology and antimicrobials · 2025Pooled it
- Vegetable Extracts and Nutrients Useful in the Recovery fromMolecules (Basel, Switzerland) · 2021Pooled it
- Association of Helicobacter pylori infection with coronary artery disease: is Helicobacter pylori a risk factor?TheScientificWorldJournal · 2014Trial
- Research advances in the pathogenesis and therapeutic interventions of Helicobacter pylori and atrial fibrillation.Frontiers in cardiovascular medicine · 2025Review
- Risk of Ischemic Stroke in Relation toGut and liver · 2024Observational
- Relationship between active Helicobacter pylori infection and risk factors of cardiovascular diseases, a cross-sectional hospital-based study in a Sub-Saharan setting.BMC infectious diseases · 2022Article
- Impact ofMicroorganisms · 2021Review
- Relationship BetweenInternational journal of general medicine · 2021Review
- Cholesteryl α-D-glucoside 6-acyltransferase enhances the adhesion of Helicobacter pylori to gastric epithelium.Communications biology · 2020Article
- Seroprevalence ofInternational journal of general medicine · 2020Article
- Helicobacter pylori eradication in the management of glaucoma.Caspian journal of internal medicine · 2020Article
- Bacterial infections are associated with cardiovascular disease in Iran: a meta-analysis.Archives of medical science : AMS · 2019Article
- Review
- Association ofMedical journal of the Islamic Republic of Iran · 2018Article
- Article
- Association Between Helicobacter Pylori Infection and Long-term Outcome in Patients with Drug-eluting Stent Implantation.Scientific reports · 2017Article
- Association betweenExperimental and therapeutic medicine · 2017Article
- Article
- Association between Bacterial Infection and Peripheral Vascular Disease: A Review.The International journal of angiology : official publication of the International College of Angiology, Inc · 2016Review
- Helicobacter pylori vs coronary heart disease - searching for connections.World journal of cardiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is still controversy about association of Helicobacter pylori (H. pylori) infection with coronary heart disease (CHD). This study designed to evaluate this association in a sample of Iranians Population.
methodsMedical and drug history as well as fasting blood samples of 112 consecutive patients who were candidate for coronary angiography were taken on catheterization day. Fasting blood samples were used to measure C-reactive protein (CRP), anti H. pylori immunoglobulin G (anti H. pylori IgG) and interlukine-6 (IL6). According to angiography reports, participants were divided into patients with (n = 62) or without CHD (n = 43). To compare the association between H. pylori infection with CHD, multivariate logistic regression tests were used by adjusting sex and age, age and sex plus history of diabetes mellitus (DM), Dyslipidemia (DLP), and/or hypertension (HTN), CRP status and IL-6 level.
resultsSixty two patients with CHD and 43 participants without CHD were enrolled in the present study. The mean ages of patients with and without CHD were 62.4 261 9.5 and 59.0 261 10.5 years respectively. Multivariate logistic regression analysis after adjusting for history of DM and/or DLP and/or HTN plus CRP status and IL-6 level showed significant association of H. pylori infection with CHD (OR 3.18, 95%CI 1.08-9.40).
conclusionH. pylori infection is one of the probable risk factors for CHD independent of history of DM, DLP, HTN, CRP status and IL-6 level.
Indexed as
Identifiers
23056092PMC3448393W1898958279What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.