ArticleFrontiers in neuroanatomy2012
Dorsal lateral geniculate substructure in the long-evans rat: a cholera toxin B subunit study.
Article in Frontiers in neuroanatomy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Development of ocular dominance columns across rodents and other species: revisiting the concept of critical period plasticity.Frontiers in neural circuits · 2024Review
- Temporal and spatial tuning of dorsal lateral geniculate nucleus neurons in unanesthetized rats.Journal of neurophysiology · 2016Article
- Oscillatory entrainment of primary somatosensory cortex encodes visual control of tactile processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
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2 authors.
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Abstract
The pigmented rat is an increasingly important model in visual neuroscience research, yet the lamination of retinal projections in the dLGN has not been examined in sufficient detail. From previous studies it was known that most of the rat dLGN receives monocular input from the contralateral eye, with a small island receiving predominantly ipsilateral projections. Here we revisit the question using cholera toxin B subunit, a tracer that efficiently fills retinal terminals after intra-ocular injection. We imaged retinal termini throughout the dLGN at 0.5 μm resolution and traced areas of ipsilateral and contralateral terminals to obtain a high resolution 3D reconstruction of the projection pattern. Retinal termini in the dLGN are well segregated by eye of origin, as expected. We find, however, that the ipsilateral projections form multiple discrete projection zones in three dimensions, not the single island previously described. It remains to be determined whether these subdomains represent distinct functional sublaminae, as is the case in other mammals.
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