ArticleExperimental neurobiology2012
Serotonin and synaptic transmission at invertebrate neuromuscular junctions.
Article in Experimental neurobiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 61 citations in OpenAlex.
- Peptidergic Modulation of the Lobster Cardiac System Has Opposing Action on Neurons and Muscles.Integrative organismal biology (Oxford, England) · 2025Article
- Effects of Essential Oils on Biological Characteristics and Potential Molecular Targets inPlants (Basel, Switzerland) · 2024Article
- Role of the Neuroendocrine System of Marine Bivalves in Their Response to Hypoxia.International journal of molecular sciences · 2023Review
- Histamine and gamma-aminobutyric acid in the nervous system of Pygospio elegans (Annelida: Spionidae): structure and recovery during reparative regeneration.BMC zoology · 2022Article
- Regulation ofiScience · 2022Article
- The development of early pioneer neurons in the annelid Malacoceros fuliginosus.BMC evolutionary biology · 2020Article
- The Effect of Bacterial Endotoxin LPS on Serotonergic Modulation of Glutamatergic Synaptic Transmission.Biology · 2020Article
- Article
- Serotonin in Animal Cognition and Behavior.International journal of molecular sciences · 2020Review
- Unique pharmacological properties of serotoninergic G-protein coupled receptors from cestodes.PLoS neglected tropical diseases · 2018Article
- Modulatory Action by the Serotonergic System: Behavior and Neurophysiology in Drosophila melanogaster.Neural plasticity · 2016Article
- Distinct Regulation of Transmitter Release at the Drosophila NMJ by Different Isoforms of nemy.PloS one · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The serotonergic system in vertebrates and invertebrates has been a focus for over 50 years and will likely continue in the future. Recently, genomic analysis and discovery of alternative splicing and differential expression in tissues have increased the knowledge of serotonin (5-HT) receptor types. Comparative studies can provide useful insights to the wide variety of mechanistic actions of 5-HT responsible for behaviors regulated or modified by 5-HT. To determine cellular responses and influences on neural systems as well as the efferent control of behaviors by the motor units, preparations amenable to detailed studies of synapses are beneficial as working models. The invertebrate neuromuscular junctions (NMJs) offer some unique advantages for such investigations; action of 5-HT at crustacean NMJs has been widely studied, and leech and Aplysia continue to be key organisms. However, there are few studies in insects likely due to the focus in modulation within the CNS and lack of evidence of substantial action of 5-HT at the Drosophila NMJs. There are only a few reports in gastropods and annelids as well as other invertebrates. In this review we highlight some of the key findings of 5-HT actions and receptor types associated at NMJs in a variety of invertebrate preparations in hopes that future studies will build on this knowledge base.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.