Evidence map›Paper›PMID 23055754›Full record

ArticleInfection and drug resistance2012

Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance.

Luke F Chen, Deverick J Anderson, David L Paterson

Abstract read
In one paragraph

Article in Infection and drug resistance, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Use of MALDI-TOF VITEK MS for rapid and efficient identification of KPC-type carbapenemases in Enterobacterales carrying the Tn4401a transposon.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  4. Article
  5. Bacteriophage treatment is effective against carbapenem-resistantAntimicrobial agents and chemotherapy · 2025
    Article
  6. Gas Chromatography-Ion Mobility Spectrometry Reveals Acetoin as a Biomarker for Carbapenemase-Producing Klebsiella pneumoniae.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  7. Observational
  8. Carbapenemase ProducingAntibiotics (Basel, Switzerland) · 2021
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Influence of substrates and inhibitors on the structure ofExperimental biology and medicine (Maywood, N.J.) · 2019
    Review
  16. Article
  17. Article
  18. Risk Factors for Carbapenem-resistantChinese medical journal · 2018
    Article
  19. Article
  20. Synergistic activity of synthetic N-terminal peptide of human lactoferrin in combination with various antibiotics against carbapenem-resistant Klebsiella pneumoniae strains.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luke F ChenDuke Program for Infection Prevention and Healthcare Epidemiology, Durham, NC, USA ; Duke Infection Control Outreach Network, Durham, NC, USA ; Duke University Prevention Epicenter Program, Durham, NC, USA ; Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Deverick J Anderson
David L Paterson

Funding

Clinical and Molecular Epidemiology of Multidrug-Resistant Organisms in a CommuniK23AI095357 · NIAID · DUKE UNIVERSITY · PI ANDERSON, DEVERICK JOHN · 2011 to 2015
$644k
NIAID NIH HHS K23 AI095357
6 · The paper itself

Abstract

Klebsiella pneumoniae carbapenemases (KPCs) confer resistance to nearly all β-lactams. This broad-spectrum drug resistance mechanism has rapidly spread in the United States and is reportedly increasing elsewhere in the world. Thus, the emergence of KPC resistance is a major threat to global health. This article reviews the epidemiology and provides an overview of the dissemination of KPC-producing organisms.

Indexed as

beta-lactam resistancecarbapenemasedrug resistanceepidemiologytreatment failure

Identifiers

PMID23055754
PMCPMC3460674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.