ArticlePatient preference and adherence2012
The roles of past behavior and health beliefs in predicting medication adherence to a statin regimen.
Article in Patient preference and adherence, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04458766 (The Use of Mobile Health Technology and Behavioral Economics to Encourage Adherence to Statins in Adolescents With Familial Hypercholesterolemia), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Use of Mobile Health Technology and Behavioral Economics to Encourage Adherence to Statins in Adolescents With Familial Hypercholesterolemia
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Social determinants of health in electronic health records and their impact on analysis and risk prediction: A systematic review.Journal of the American Medical Informatics Association : JAMIA · 2020Pooled it
- Factors Associated With Discontinuation of Tuberculosis Preventive Treatment: Post Hoc Analysis of 2 Randomized, Controlled Trials.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Trial
- Early Detection of Lower Adherence to Long-Term e-Diary Recording: A Checkpoint to Target Early Educational Intervention in Seasonal Allergic Rhinitis?Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026Observational
- Article
- Internet literacy and health related quality of life in urban Korean adults mediated by medication adherence and ego-resiliency.Scientific reports · 2025Article
- The Use of Mobile Health Technology and Behavioral Economics to Encourage Adherence to Statins and Blood Pressure-Lowering Medication in Adolescents with Familial Hypercholesterolemia or Hypertension: Protocol for a Pre-Post Cohort Study.JMIR research protocols · 2025Article
- A Systematic Review Uncovering Modifiable Influences on Statin Adherence.Patient preference and adherence · 2025Review
- Model-based estimation of individual-level social determinants of health and its applications in All of Us.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Article
- Towards better reporting of the proportion of days covered method in cardiovascular medication adherence: A scoping review and new tool TEN-SPIDERS.British journal of clinical pharmacology · 2022Article
- Identifying individual social risk factors using unstructured data in electronic health records and their relationship with adverse clinical outcomes.SSM - population health · 2022Article
- Prior Cardiovascular Treatments-A Key Characteristic in Determining Medication Adherence After an Acute Myocardial Infarction.Frontiers in pharmacology · 2022Article
- Predicting medication adherence using ensemble learning and deep learning models with large scale healthcare data.Scientific reports · 2021Article
- Immigrants, Ethnicity, and Adherence to Secondary Cardiac Prevention Therapy: A Substudy of the ISLAND Trial.CJC open · 2021Article
- Identifying adherent patients to newly initiated statins using previous adherence to chronic medications.Journal of managed care & specialty pharmacy · 2021Article
- Article
- Development and validation of CF-Medication Beliefs Questionnaire: A mixed-methods approach.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2017Article
- Article
- Risk of Nondherence to Diabetes Medications Among Medicare Advantage Enrollees: Development of a Validated Risk Prediction Tool.Journal of managed care & specialty pharmacy · 2016Observational
- Observing versus Predicting: Initial Patterns of Filling Predict Long-Term Adherence More Accurately Than High-Dimensional Modeling Techniques.Health services research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCurrent medication-adherence predictive tools are based on patient medication-taking beliefs, but studying past behavior may now be a more explanatory and accessible method. This study will evaluate if past medication-refill behavior for a statin regimen is more predictive of medication adherence than patient medication-taking health beliefs. PATIENTS AND
methodsThis prospective longitudinal study was implemented in a national managed care plan in the United States. A group of 1433 statin patients were identified and followed for 6 months. Medication-taking health beliefs, collected from self-reported mail questionnaires, and past medication-refill behavior, using proportion of days covered (PDC), were collected prior to 6-month follow-up. Outcomes were measured using categorical PDC variable (of adherence, PDC ≥ 85%, versus nonadherence, PDC < 85%), with model fit estimated using receiver operator characteristic analysis.
resultsThe area under the receiver operator characteristic curve for past behavior (A(z) = 0.78) was significantly greater (P < 0.05) than for patient health beliefs (A(z) = 0.69), indicating that past prescription-refill behavior is a better predictor of medication adherence than prospective health beliefs. Among health beliefs, the factor most related to medication adherence was behavioral intent (odds ratio, 5.12; 95% confidence interval, 1.84 to 15.06). The factor most strongly related to behavioral intent was impact of regimen on daily routine (odds ratio, 3.3; 95% confidence interval, 1.41 to 7.74).
conclusionElectronic medical records and community health-information networks may make past prescription-refill rates more accessible and assist physicians with managing medication-regimen adherence. Health beliefs, however, may still play an important role in influencing medication-taking behaviors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.