Evidence map›Paper›PMID 23055399›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2013

Plasmid-templated shape control of condensed DNA-block copolymer nanoparticles.

Xuan Jiang, Wei Qu, Deng Pan, Yong Ren, John-Michael Williford, Honggang Cui, Erik Luijten, Hai-Quan Mao

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Review
  2. Review
  3. Supramolecular assembly of polycation/mRNA nanoparticles and in vivo monocyte programming.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Nanotherapeutic Heterogeneity: Sources, Effects, and Solutions.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  5. Stimuli-Responsive Non-viral Nanoparticles for Gene Delivery.Handbook of experimental pharmacology · 2024
    Article
  6. Review
  7. Review
  8. Non-viral vectors for RNA delivery.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Review
  9. Biomedical nanoparticle design: What we can learn from viruses.Journal of controlled release : official journal of the Controlled Release Society · 2021
    Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Ultrasound-enhanced gene delivery to alfalfa cells by hPAMAM dendrimer nanoparticles.Turkish journal of biology = Turk biyoloji dergisi · 2018
    Article
  20. Gene delivery nanoparticles to modulate angiogenesis.Advanced drug delivery reviews · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xuan JiangDepartment of Materials Science and Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA.
Wei Qu
Deng Pan
Yong Ren
John-Michael Williford
Honggang Cui
Erik Luijten
Hai-Quan Mao

Funding

ValidationU54CA151838 · NCI · JOHNS HOPKINS UNIVERSITY · PI LEVITSKY, HYAM ISAAC · 2010 to 2014
$11.9M
Non-viral Liver-targeted Gene DeliveryR01DK068399 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MAO, HAI-QUAN · 2006 to 2010
$1.4M
Biodegradable Micelles for Liver-Targeted Gene DeliveryR01GM073937 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI MAO, HAI-QUAN · 2008 to 2011
$1.4M
Delivery of Shaped siRNA Nanoparticles by Retrograde Intrabiliary InfusionR21EB015152 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI MAO, HAI-QUAN · 2012 to 2013
$437k
Shape Control and Transfection of Self-assembled Polymer-DNA NanoparticlesR21EB013274 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI MAO, HAI-QUAN · 2012 to 2013
$431k
NCI NIH HHS U54 CA151838NCI NIH HHS U54CA151838NIBIB NIH HHS R21 EB013274NIBIB NIH HHS R21EB013274NIBIB NIH HHS R21 EB015152NIDDK NIH HHS R01 DK068399NIDDK NIH HHS R01DK068399NIGMS NIH HHS R01 GM073937NIGMS NIH HHS R01GM073937
6 · The paper itself

Abstract

DNA-containing micellar nanoparticles with distinctly different and highly uniform morphologies are prepared via condensation of plasmid DNA with a block copolymer of polyethylene glycol and a polycation in solvents of different polarity. Molecular dynamics simulations explain the underlying mechanism.

Indexed as

AmidesDimethylformamideDNAMicellesNanoparticlesPhosphoric AcidsPlasmidsPolyethylene GlycolsPolymersWaterAmidesDimethylformamideDNAMicellesphosphoramidic acidPhosphoric AcidsPolyethylene GlycolsPolymersWater

Identifiers

PMID23055399
PMCPMC3918481

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.