Evidence map›Paper›PMID 23055232›Full record

ArticleDemography2012

The DYNAMO-HIA model: an efficient implementation of a risk factor/chronic disease Markov model for use in Health Impact Assessment (HIA).

Hendriek C Boshuizen, Stefan K Lhachimi, Pieter H M van Baal, Rudolf T Hoogenveen, Henriette A Smit, Johan P Mackenbach, Wilma J Nusselder

Abstract read
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In one paragraph

Article in Demography, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Cost-Effectiveness of Personalised Nutrition in Adults With Overweight and Obesity: PREVENTOMICS Studies in Poland and the UK.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
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  11. HIA and EIA Are Different, but Maybe Not in the Way We Thought They Were: A Bibliometric Analysis.International journal of environmental research and public health · 2021
    Article
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  18. Economic Evaluation of Five Tobacco Control Policies Across Seven European Countries.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hendriek C BoshuizenDepartment of Statistics and Mathematical Modelling, National Institute of Public Health and the Environment, Bilthoven, The Netherlands. hendriek.boshuizen@rivm.nl
Stefan K Lhachimi
Pieter H M van Baal
Rudolf T Hoogenveen
Henriette A Smit
Johan P Mackenbach
Wilma J Nusselder

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Health Impact Assessment (HIA), or priority-setting for health policy, effects of risk factors (exposures) on health need to be modeled, such as with a Markov model, in which exposure influences mortality and disease incidence rates. Because many risk factors are related to a variety of chronic diseases, these Markov models potentially contain a large number of states (risk factor and disease combinations), providing a challenge both technically (keeping down execution time and memory use) and practically (estimating the model parameters and retaining transparency). To meet this challenge, we propose an approach that combines micro-simulation of the exposure information with macro-simulation of the diseases and survival. This approach allows users to simulate exposure in detail while avoiding the need for large simulated populations because of the relative rareness of chronic disease events. Further efficiency is gained by splitting the disease state space into smaller spaces, each of which contains a cluster of diseases that is independent of the other clusters. The challenge of feasible input data requirements is met by including parameter calculation routines, which use marginal population data to estimate the transitions between states. As an illustration, we present the recently developed model DYNAMO-HIA (DYNAMIC MODEL for Health Impact Assessment) that implements this approach.

Indexed as

Markov ChainsAdultAgedAged, 80 and overChronic DiseaseDiabetes MellitusFemaleHealth BehaviorHealth Impact AssessmentHumansIncidenceLife StyleMaleMiddle AgedObesityRisk Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.