Evidence map›Paper›PMID 23055077›Full record

ArticleJournal of the American Society for Mass Spectrometry2012

Mannose7 glycan isomer characterization by IMS-MS/MS analysis.

Feifei Zhu, Sunyoung Lee, Stephen J Valentine, James P Reilly, David E Clemmer

Abstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 70 citations in OpenAlex.

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  19. Cryogenic Vibrational Spectroscopy Provides Unique Fingerprints for Glycan Identification.Journal of the American Society for Mass Spectrometry · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Feifei ZhuDepartment of Chemistry, Indiana University, 800 Kirkwood Ave., Bloomington, IN 47405, USA.
Sunyoung Lee
Stephen J Valentine
James P Reilly
David E Clemmer
Indiana University Bloomington · US

Funding

Developing high-throughput IMS-MS and IMS-IMS-MS techniques for glycomics analysiR01GM093322 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI CLEMMER, DAVID E., MECHREF, YEHIA · 2010 to 2013
$1.1M
New Ion Mobility/Photodissociation Techniques for Analyzing GlycansRC1GM090797 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI CLEMMER, DAVID E. · 2009 to 2010
$955k
NIGMS NIH HHS 1RC1GM090797-01NIGMS NIH HHS 5R01GM93322NIGMS NIH HHS R01 GM093322NIGMS NIH HHS RC1 GM090797
6 · The paper itself

Abstract

The isomers of the Man(7)GlcNAc(2) glycan obtained from bovine ribonuclease B have been characterized by ion mobility spectrometry-tandem mass spectrometry (IMS-MS/MS). In these experiments, [Man7 + 2Na](2+) precursors having different mobilities are selected by ion mobility spectrometry and analyzed by MS/MS techniques in an ion trap. The fragmentation spectra obtained for various precursor ions are specific, suggesting the isolation or enrichment of different glycan isomers. One fragment ion with a mass-to-charge ratio (m/z) of 903.8 is found to correspond to the loss of an internal mannose residue of a specific isomer. Extracted fragment ion drift time distributions (XFIDTDs) yield distinctive precursor ion drift time profiles indicating the existence of four separate isomers as proposed previously.

Indexed as

AnimalsCarbohydrate ConformationCattleEquipment DesignIonsIsomerismMannoseModels, MolecularPolysaccharidesRibonucleasesTandem Mass SpectrometryIonsMannosePolysaccharidesribonuclease BRibonucleases

Identifiers

PMID23055077
PMCPMC3515714
OpenAlexW1986504194

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.