ArticleProceedings. Biological sciences2012
Sperm-related phenotypes implicated in both maintenance and breakdown of a natural species barrier in the house mouse.
Article in Proceedings. Biological sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Beyond the Prdm9 model: independent evolution of hybrid male sterility in house mice.Heredity · 2026Article
- Carriage of Antibiotic-ResistantVeterinary medicine international · 2026Article
- The Shapes of Clines and Wavefronts.Molecular ecology · 2025Review
- Shifting focus from resistance to disease tolerance: A review on hybrid house mice.Ecology and evolution · 2022Review
- Y chromosomal noncoding RNAs regulate autosomal gene expression via piRNAs in mouse testis.BMC biology · 2021Article
- Genome-wide ancestry and introgression in a Zambian baboon hybrid zone.Molecular ecology · 2021Article
- Prdm9 Intersubspecific Interactions in Hybrid Male Sterility of House Mouse.Molecular biology and evolution · 2020Article
- The role of copy-number variation in the reinforcement of sexual isolation between the two European subspecies of the house mouse.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- Disrupted Gene Networks in Subfertile Hybrid House Mice.Molecular biology and evolution · 2020Article
- Phenotypic effects of the Y chromosome are variable and structured in hybrids among house mouse recombinant lines.Ecology and evolution · 2019Article
- Differential sperm-egg interactions in experimental pairings between two subspecies and their hybrids in a passerine bird.Ecology and evolution · 2018Article
- The genomic impact of historical hybridization with massive mitochondrial DNA introgression.Genome biology · 2018Article
- Genetic vs environment influences on house mouse hybrid zone in Iran.Journal, genetic engineering & biotechnology · 2017Article
- Speciation and reduced hybrid female fertility in house mice.Evolution; international journal of organic evolution · 2015Article
- Tracing reinforcement through asymmetrical partner preference in the European common vole Microtus arvalis.BMC evolutionary biology · 2015Article
- Seeking signatures of reinforcement at the genetic level: a hitchhiking mapping and candidate gene approach in the house mouse.Molecular ecology · 2015Article
- Functional organization of the genome may shape the species boundary in the house mouse.Molecular biology and evolution · 2015Article
- Murine cytomegalovirus is not restricted to the house mouse Mus musculus domesticus: prevalence and genetic diversity in the European house mouse hybrid zone.Journal of virology · 2015Article
- Article
- The uncharacterized gene 1700093K21Rik and flanking regions are correlated with reproductive isolation in the house mouse, Mus musculus.Mammalian genome : official journal of the International Mammalian Genome Society · 2014Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The house mouse hybrid zone (HMHZ) is a species barrier thought to be maintained by a balance between dispersal and natural selection against hybrids. While the HMHZ is characterized by frequency discontinuities for some sex chromosome markers, there is an unexpected large-scale regional introgression of a Y chromosome across the barrier, in defiance of Haldane's rule. Recent work suggests that a major force maintaining the species barrier acts through sperm traits. Here, we test whether the Y chromosome penetration of the species barrier acts through sperm traits by assessing sperm characteristics of wild-caught males directly in a field laboratory set up in a Y introgression region of the HMHZ, later calculating the hybrid index of each male using 1401 diagnostic single nucleotide polymorphisms (SNPs). We found that both sperm count (SC) and sperm velocity were significantly reduced across the natural spectrum of hybrids. However, SC was more than rescued in the presence of the invading Y. Our results imply an asymmetric advantage for Y chromosome introgression consistent with the observed large-scale introgression. We suggest that selection on sperm-related traits probably explains a large component of patterns observed in the natural hybrid zone, including the Y chromosome penetration.
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